The prevalence of autistic spectrum disorders in adolescents with a history of specific language impairment (SLI)
The prevalence of autistic spectrum disorders in adolescents with a history of specific language impairment (SLI)
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DOI：
10.1111/j.1469-7610.2005.01584.x
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发表时间：
2006-06-01
影响因子：
7.6
通讯作者：
Botting, Nicola
中科院分区：
文献类型：
--
作者：
Conti-Ramsden, Gina;Simkin, Zoe;Botting, Nicola
背景：传统上，自闭症和特定语言障碍(SLI)被认为是不同的疾病，但最近有证据表明它们之间存在更密切的联系：一组常见的语言问题，特别是接受性语言障碍，以及包括语用语言障碍在内的中间病例的存在。本研究旨在调查有系统性红斑狼疮病史的青少年中自闭症谱系障碍的患病率。方法：对76例确诊为系统性红斑狼疮病史的14岁儿童进行自闭症谱系障碍检查。研究采用了多种工具，包括自闭症诊断访谈修订版(ADI-R)、自闭症诊断观察表(ADOS)和家族史访谈(FHI)。结果：自闭症谱系障碍在青少年SLI患者中的患病率为3.9%，约为一般人群预期的10倍。此外，有SLI病史的年轻人中，有更多的人只表现出一些自闭症谱系症状或表现为轻度症状。结论：患有SLI的年轻人患自闭症的风险增加。这种风险的规模是相当大的。此外，更大比例(四分之一的人)出现了一些与自闭症谱系障碍相一致的行为。
Background: Traditionally, autism and specific language impairment (SLI) have been regarded as distinct disorders but, more recently, evidence has been put forward for a closer link between them: a common set of language problems, in particular receptive language difficulties and the existence of intermediate cases including pragmatic language impairment. The present study aimed to examine the prevalence of autism spectrum disorders in a large sample of adolescents with a history of SLI. Method: The presence of autism spectrum disorders was examined in seventy-six 14-year-olds with a confirmed history of SLI. A variety of instruments were employed, including the Autism Diagnostic Interview-Revised (ADI-R), the Autism Diagnostic Observation Schedule (ADOS) and the Family History Interview (FHI). Results: The prevalence of autism spectrum disorders in young people with SLI was found to be 3.9%, about 10 times what would be expected from the general population. In addition, a much larger number of young people with a history of SLI showed only some autism spectrum symptoms or showed them in a mild form. Conclusions: Young people with SLI have an increased risk of autism. The magnitude of this risk is considerable. In addition, a larger proportion ( a quarter of individuals) present with a number of behaviours consistent with autism spectrum disorders.