Suppression of cardiac motion artifacts in sequential intracoronary optical coherence images
Suppression of cardiac motion artifacts in sequential intracoronary optical coherence images
复制标题
连续冠状动脉内光学相干图像中心脏运动伪影的抑制
DOI：
10.1166/jmihi.2016.1891
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发表时间：
2016
影响因子：
--
通讯作者：
李梦婵
中科院分区：
文献类型：
--
作者：
孙正;李梦婵
研究背景冠状动脉内光学相干断层扫描(IC-OCT)是一种介入性成像技术，几十年来一直被用于心血管疾病的临床诊断。心脏运动和脉动血流引起的运动伪影一直阻碍着通过在血管腔内连续拉回成像导管而获得的连续IC-OCT图像的可视化。基于灰度特征的循环变化或管腔轮廓质心沿整个图像序列的位置来检测暗示心脏相位的信号。结果临床采集的活体数据的实验结果表明，选通子序列的平均帧间差值明显低于原序列。结论基于管腔轮廓的方法比基于强度的方法更适合于强度特征变化不明显的图像序列。
BackgroundIntracoronary optical coherence tomography (IC-OCT), an interventional imaging modality, has been used in clinical diagnosis of cardiac vessel diseases for decades. Motion artifacts caused by cardiac motion and pulsatile blood flow always hamper the visualization of sequential IC-OCT images acquired by continuously pulling back the imaging catheter within the vascular lumen.MethodSuppression of cardiac motion artifacts in an IC-OCT image sequence was addressed in this study. A signal implying cardiac phases was detected based on the cyclic variation of gray-scale features or the location of the lumen contour centroid along the overall image sequence. The local extrema of the signal were detected according to which the gating frames were selected.ResultThe experimental results of clinically acquired in vivo data show that the average inter-frame difference of the gated subsequence is obviously lower than the original one. The visualization of longitudinal cuts is improved significantly.ConclusionLumen-contour based scheme is more suitable for those image sequences where the variation of intensity features is not apparent than the intensity-based one.