Effects of nutritional stress during different developmental periods on song and the hypothalamic-pituitary-adrenal axis in zebra finches
Effects of nutritional stress during different developmental periods on song and the hypothalamic-pituitary-adrenal axis in zebra finches
复制标题
DOI：
10.1016/j.yhbeh.2013.12.013
复制
发表时间：
2014-03-01
影响因子：
3.5
通讯作者：
MacDougall-Shackleton, S. A.
中科院分区：
文献类型：
--
作者：
Kriengwatana, B.;Wada, H.;MacDougall-Shackleton, S. A.
在鸣禽中，发育压力会影响歌唱的学习和产生。下丘脑-垂体-肾上腺(HPA)轴功能改变导致皮质酮(CORT)升高可能是这种影响的原因之一。我们研究了发育状况是否影响成人歌曲和HPA轴功能之间的联系，以及营养独立前后的营养应激是否对歌曲学习和/或发声有明显影响。斑雀(Taeniopygia Guttata)在持续的高(HH)或低(LL)食物条件下饲养，直到孵化后第62天(PhD)，或在PhD 34时从高到低(HL)或从高到低(HL)切换(LH)。这首歌是在成年时录制的。我们评估了皮质醇对发育过程中的处理和成年期地塞米松(DEX)和促肾上腺皮质激素(ACTH)挑战的反应。在这两个发育阶段，营养应激都不影响歌曲学习和发声能力。在发育过程中，营养应激使基线皮质醇升高。营养应激也增加了只在幼年阶段经历应激的鸟类的皮质醇分泌率(HL组)。在注射ACTH后，LL组雏鸡的CURT水平低于其他组，但营养应激对DEX的反应没有影响。因此，我们的发现表明，发育应激可以影响HPA功能，而不同时影响SING。(C)2014 Elsevier Inc.保留所有权利。
In songbirds, developmental stress affects song learning and production. Altered hypothalamic-pituitary-adrenal (HPA) axis function resulting in elevated corticosterone (CORT) may contribute to this effect. We examined whether developmental conditions affected the association between adult song and HPA axis function, and whether nutritional stress before and after nutritional independence has distinct effects on song learning and/or vocal performance. Zebra finches (Taeniopygia guttata) were raised in consistently high (HH) or low (LL) food conditions until post-hatch day (PHD) 62, or were switched from high to low conditions (HL) or vice versa (LH) at PHD 34. Song was recorded in adulthood. We assessed the response of CORT to handling during development and to dexamethasone (DEX) and adrenocorticotropic hormone (ACTH) challenges during adulthood. Song learning and vocal performance were not affected by nutritional stress at either developmental stage. Nutritional stress elevated baseline CORT during development. Nutritional stress also increased rate of CORT secretion in birds that experienced stress only in the juvenile phase (HL group). Birds in the LL group had lower CURT levels after injection of ACTH compared to the other groups, however there was no effect of nutritional stress on the response to DEX Thus, our findings indicate that developmental stress can affect HPA function without concurrently affecting song. (C) 2014 Elsevier Inc. All rights reserved.