The thylakoid membranes of cyanobacteria: structure, dynamics and function
The thylakoid membranes of cyanobacteria: structure, dynamics and function
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DOI：
10.1071/pp99027
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发表时间：
1999-01-01
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影响因子：
--
通讯作者：
Mullineaux, CW
中科院分区：
文献类型：
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作者：
Mullineaux, CW
近年来，在确定光合复合物的三维结构方面取得了显著的进展。一个新的挑战正在出现：我们能否理解这些复合物在完整的光合膜中的组织和相互作用？完整的膜是复杂的动态系统。如果我们要了解完整膜的功能，我们需要了解复合物的组织，它们如何在膜中扩散和相互作用，它们如何组装，修复和分解，以及它们的功能如何调节。蓝细菌作为模型系统有一些关键的优势。集胞藻6803基因组的完整测序，加上集胞藻（和某些其他蓝藻）的遗传操作的便利性，为我们研究光合生物提供了一个独特的工具。此外，一些蓝藻有一个非常简单，规则的类囊体膜结构。这些蓝藻光合膜的独特几何结构将极大地促进膜功能的生物物理研究。本文综述了近年来蓝藻类囊体膜的结构、功能和动力学的研究进展，并提出了一些有待解决的问题和可能的解决途径。
In recent years there has been remarkable progress in determining the three-dimensional structures of photosynthetic complexes. A new challenge is emerging: can we understand the organisation and interaction of those complexes in the intact photosynthetic membrane? Intact membranes are complex, dynamic systems. If we are to understand the function of the intact membrane, we will need to understand the organisation of the complexes, how they can diffuse and interact in the membrane, how they are assembled, repaired and broken down, and how their function is regulated. Cyanobacteria have some crucial advantages as model systems. The complete sequencing of the Synechocystis 6803 genome, coupled with the ease of genetic manipulation of Synechocystis (and certain other cyanobacteria) have given us a unique tool for studying a photosynthetic organism. Furthermore, some cyanobacteria have a very simple, regular thylakoid membrane structure. The unique geometry of photosynthetic membranes of these cyanobacteria will greatly facilitate biophysical studies of membrane function. This review summarises recent progress in understanding the structure, function and dynamics of cyanobacterial thylakoid membranes, highlights the questions that remain to be answered and suggests some possible approaches towards solving those questions.