Premotor cortex mediates perceptual performance
Premotor cortex mediates perceptual performance
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DOI：
10.1016/j.neuroimage.2010.02.027
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发表时间：
2010-06-01
期刊：
影响因子：
5.7
通讯作者：
Kawato, Mitsuo
中科院分区：
文献类型：
--
作者：
Callan, Daniel;Callan, Akiko;Kawato, Mitsuo
长期以来，人们一直提出用发音目标来调节感知。例子包括言语知觉的直接现实主义和建构主义(综合分析)理论。尽管与动作产生有关的大脑区域的活动已经被证明存在于动作观察(镜像神经元系统)中，但这一活动与知觉表现的关系在事件水平上还没有得到清楚的证明。为此，我们使用功能磁共振成像、功能磁共振成像和脑磁图来测量大脑活动，以判断噪声任务中听觉语音识别的正确和错误尝试。FMRI分析显示，运动前皮质包括邻近的Broca区额盖部分(PMC/Broca‘s)，在涉及相同语音刺激(潜在镜像系统位置)的知觉和产生任务中的活动，在正确的知觉识别试验中显著高于错误的知觉识别试验。使用分层变分贝叶斯信号源分析技术对定位于PMC/Broca的MEG电流进行的单次试验的时频分析显示，在刺激呈现前后，事件相关同步ERS和去同步ERD显著高于α、β和伽马频率范围内的不正确试验。总之，这些fMRI和MEG结果与发音过程有助于促进知觉表现的假设是一致的，同时进一步消除了人们的担忧，即腹侧PMC/Broca(镜像系统)中的活动只是知觉动作的隐蔽产生的产物。在刺激开始前发现的绩效预测活动以及与任务难度有关的活动，而不是刺激中可获得的信息，与建构主义的知觉理论是一致的，而与知觉的直接现实主义理论相反。(C)2010 Elsevier Inc.保留所有权利。
Articulatory goals have long been proposed to mediate perception. Examples include direct realist and constructivist (analysis by synthesis) theories of speech perception. Although the activity in brain regions involved with action production has been shown to be present during action observation (Mirror Neuron System), the relationship of this activity to perceptual performance has not been clearly demonstrated at the event level. To this end we used functional magnetic resonance imaging fMRI and magnetoencephalography MEG to measure brain activity for correct and incorrect trials of an auditory phonetic identification in noise task. FMRI analysis revealed activity in the premotor cortex including the neighboring frontal opercular part of Broca's area (PMC/Broca's) for both perception and production tasks involving the same phonetic stimuli (potential mirror system site) that was significantly greater for correct over incorrect perceptual identification trials. Time-frequency analysis of single trials conducted over MEG current localized to PMC/Broca's using a hierarchical variational Bayesian source analysis technique revealed significantly greater event-related synchronization ERS and desynchronization ERD for correct over incorrect trials in the alpha, beta, and gamma frequency range prior to and after stimulus presentation. Together, these fMRI and MEG results are consistent with the hypothesis that articulatory processes serve to facilitate perceptual performance, while further dispelling concerns that activity found in ventral PMC/Broca's (mirror system) is merely a product of covert production of the perceived action. The finding of performance predictive activity prior to stimulus onset as well as activity related to task difficulty instead of information available in stimulation are consistent with constructivist and contrary to direct realist theories of perception. (C) 2010 Elsevier Inc. All rights reserved.