Alcohol exposure and outcomes in trauma patients.
Alcohol exposure and outcomes in trauma patients.
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DOI：
10.1007/s00068-010-0038-5
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发表时间：
2011-04
影响因子：
2.1
通讯作者：
Rhee, P.
中科院分区：
文献类型：
--
作者：
Hadjizacharia, P.;O'Keeffe, T.;Plurad, D. S.;Green, D. J.;Brown, C. V. R.;Chan, L. S.;Demetriades, D.;Rhee, P.
确定创伤患者饮酒后的损伤模式、并发症和死亡率。对2002年1月1日至2005年12月31日期间接受毒理学筛查的所有患者在美国外科医师学会（ACS）I级中心的创伤登记处进行了查询。酒精阳性（AP）患者与对照组患者匹配，对照组患者使用年龄，性别，机制，损伤严重程度评分（ISS），头部简明损伤量表（AIS），胸部AIS，腹部AIS和四肢AIS进行完全阴性筛查（AN）。比较两组的损伤和结局。多达5，317名患者有毒理学数据，其中471名（8.9%）有酒精筛查阳性（AP）。共有386名AP患者与386名对照（AN）患者相匹配。AP组总体死亡率显著高于AN组（23 vs. 13%; p < 0.001），ISS分层：ISS < 16（6 vs. 0.4%; p < 0.001），ISS 16-25（53 vs. 28%; p = 0.01），ISS > 25（90 vs. 67%; p = 0.01）。AP患者入院时收缩压< 90（18 vs. 10%; p < 0.001）和格拉斯哥昏迷量表（GCS）评分≤ 8（25 vs. 17%; p = 0.002）的发生率较高。AN患者的血气胸发生率显著较高（11 vs. 7%; p = 0.03），而AP患者的心脏骤停发生率较高（8 vs. 3%; p = 0.004）。重症监护室（ICU）和住院时间无差异。在创伤患者的混合人群中，AP筛查与入院低血压和GCS评分降低的发生率增加相关。在这项病例匹配研究中，酒精暴露似乎会增加受伤后的死亡率。
To determine the injury patterns, complications, and mortality after alcohol consumption in trauma patients. The Trauma Registry at an American College of Surgeons (ACS) level I center was queried for all patients with a toxicology screen admitted between 1st January 2002 and 31st December 2005. Alcohol-positive (AP) patients were matched to control patients who had a completely negative screen (AN) using age, gender, mechanism, Injury Severity Score (ISS), head Abbreviated Injury Scale (AIS), chest AIS, abdominal AIS, and extremity AIS. Injuries and outcomes were compared between the groups. As many as 5,317 patients had toxicology data, of which 471 (8.9%) had a positive alcohol screen (AP). A total of 386 AP patients were then matched to 386 control (AN) patients. The AP group had a significantly higher mortality than the AN group overall (23 vs. 13%; p < 0.001), and by ISS stratification: ISS < 16 (6 vs. 0.4%; p < 0.001), ISS 16–25 (53 vs. 28%; p = 0.01), and ISS > 25 (90 vs. 67%; p = 0.01). AP patients had a higher incidence of admission systolic blood pressure < 90 (18 vs. 10%; p < 0.001) and Glasgow Coma Scale (GCS) score ≤ 8 (25 vs. 17%; p = 0.002). AN patients had a significantly higher incidence of hemopneumothorax (11 vs. 7%; p = 0.03), while AP patients had a higher incidence of cardiac arrest (8 vs. 3%; p = 0.004). There was no difference in intensive care unit (ICU) and hospital length of stay. In a mixed population of trauma patients, an AP screen is associated with an increased incidence of admission hypotension and depressed GCS score. In this case-matched study, alcohol exposure appeared to increase mortality after injury.
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DOI：
10.1016/j.jamcollsurg.2006.02.024
发表时间：
2006-06-01
影响因子：
5.2
作者：
Plurad, D;Demetriades, D;Cryer, HG
通讯作者：
Cryer, HG
DOI：
10.1097/ta.0b013e318031aa7f
发表时间：
2007-03-01
影响因子：
--
作者：
Rootman, Daniel B.;Mustard, Robert;Ahmed, Najma
通讯作者：
Ahmed, Najma
DOI：
10.1016/0020-1383(95)00034-7
发表时间：
1995-06-01
影响因子：
2.5
作者：
BRICKLEY, MR;SHEPHERD, JP
通讯作者：
SHEPHERD, JP
DOI：
10.1097/00005373-200204000-00010
发表时间：
2002-04-01
影响因子：
--
作者：
Phelan, H;Stahls, P;Molina, PE
通讯作者：
Molina, PE
影响因子：
6
作者：
Borges, Guilherme;Cherpitel, Cheryl J.;Poznyak, Vladimir
通讯作者：
Poznyak, Vladimir