A Case of Basaloid Follicular Hamartoma
A Case of Basaloid Follicular Hamartoma
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DOI：
10.5021/ad.2010.22.2.229
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发表时间：
2010-05-01
影响因子：
1.6
通讯作者：
Ro, Byung In
中科院分区：
文献类型：
--
作者：
Go, Jae Wan;Oh, Hwa Eun;Ro, Byung In
基底细胞样滤泡错构瘤（Basaloid follicular hamartoma， BFH）是一种罕见的与附件结构相连的良性肿瘤，具有多种临床表现，可发展为基底细胞癌。BFH可以是先天性的，也可以是获得性的，先天性可进一步分为全身性和单侧型，获得性可表现为局部性和孤立性病变。先天性、全身性BFH与全身性疾病如脱发、囊性纤维化、多汗症和重症肌无力有关。相反，散发性病例为单侧或局部病变。BFH显示粗绳状和细绳状吻合的基底细胞增生，起源于毛囊，被松散的纤维间质包围。在这里，我们报告一位70岁的男性获得性孤立型BFH。（安·皮德尔22(2)229类似于2010年的231）
Basaloid follicular hamartoma (BFH), uncommon rare benign neoplasm connected to the adnexal structures, presents with multiple clinical manifestations that can develop into basal cell carcinoma. BFH may be congenital or acquired, and the congenital form can be further divided into the generalized and unilateral type, and the acquired form may present as localized and solitary lesions. Congenital, generalized BFH is associated with systemic diseases such as alopecia, cystic fibrosis, hypohidrosis, and myasthenia gravis. In contrast, sporadic cases are observed as unilateral or localized lesions. BFH shows thick cords and thin strands of anastomosing basaloid proliferations that arise from hair follicles and are enclosed by loose fibrous stroma. Here, we report a 70-year-old man with an acquired, solitary form of BFH. (Ann Dermatol 22(2) 229 similar to 231, 2010)