Temperature Sensitivity of Cardiac Function in Pelagic Fishes with Different Vertical Mobilities: Yellowfin Tuna (Thunnus albacares), Bigeye Tuna (Thunnus obesus), Mahimahi (Coryphaena hippurus), and Swordfish (Xiphias gladius)
Temperature Sensitivity of Cardiac Function in Pelagic Fishes with Different Vertical Mobilities: Yellowfin Tuna (Thunnus albacares), Bigeye Tuna (Thunnus obesus), Mahimahi (Coryphaena hippurus), and Swordfish (Xiphias gladius)
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DOI：
10.1086/597484
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发表时间：
2009-05-01
影响因子：
1.6
通讯作者：
Brill, Richard W.
中科院分区：
文献类型：
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作者：
Galli, Gina L. J.;Shiels, Holly A.;Brill, Richard W.
我们测量了温度敏感性，肾上腺素能敏感性，并依赖于肌浆网（SR）的Ca 2+从远洋鱼类具有不同的垂直流动模式：大眼金枪鱼（Thunnus obesus），黄鳍金枪鱼（Thunnus albacares），和mahimahi（Coryphaena hippurus）和一个单一的标本从旗鱼（Xiphias gladius）的心室肌。大眼金枪鱼和Mahimahi的心室肌对温度的急性降低（从26摄氏度到7摄氏度）表现出双相反应;抽搐力和动力学参数最初增加，然后下降。这种反应的幅度在大眼金枪鱼中比在Mahimahi中更大。稳态条件下，在26摄氏度，抑制SR钙释放和再摄取ryanodine和毒胡萝卜素减少抽搐力和动力学参数，分别在大眼金枪鱼。然而，在大眼金枪鱼和mahimahi的SR抑制与温度降低相关的初始肌力被取消。肾上腺素的应用完全逆转了兰尼碱和毒胡萝卜素的作用，但这种作用在低温下减弱。在黄鳍金枪鱼，温度和SR抑制有轻微的影响，抽搐力和动力学，而肾上腺素显着增加这些参数。有限的数据表明，剑鱼心室肌对急性降温、SR抑制和肾上腺素能刺激的反应方式与大眼金枪鱼心室肌相似。总的来说，我们的研究结果表明，温度敏感性，SR的依赖性，和肾上腺素敏感性的中上层鱼的心脏是物种特异性的，这些差异反映了物种特异性的垂直流动模式。
We measured the temperature sensitivity, adrenergic sensitivity, and dependence on sarcoplasmic reticulum (SR) Ca2+ of ventricular muscle from pelagic fishes with different vertical mobility patterns: bigeye tuna (Thunnus obesus), yellowfin tuna (Thunnus albacares), and mahimahi (Coryphaena hippurus) and a single specimen from swordfish (Xiphias gladius). Ventricular muscle from the bigeye tuna and mahimahi exhibited a biphasic response to an acute decrease in temperature (from 26 degrees to 7 degrees C); twitch force and kinetic parameters initially increased and then declined. The magnitude of this response was larger in the bigeye tuna than in the mahimahi. Under steady state conditions at 26 degrees C, inhibition of SR Ca2+ release and reuptake with ryanodine and thapsigargin decreased twitch force and kinetic parameters, respectively, in the bigeye tuna only. However, the initial inotropy associated with decreasing temperature was abolished by SR inhibition in both the bigeye tuna and the mahimahi. Application of adrenaline completely reversed the effects of ryanodine and thapsigargin, but this effect was diminished at cold temperatures. In the yellowfin tuna, temperature and SR inhibition had minor effects on twitch force and kinetics, while adrenaline significantly increased these parameters. Limited data suggest that swordfish ventricular muscle responds to acute temperature reduction, SR inhibition, and adrenergic stimulation in a manner similar to that of bigeye tuna ventricular muscle. In aggregate, our results show that the temperature sensitivity, SR dependence, and adrenergic sensitivity of pelagic fish hearts are species specific and that these differences reflect species-specific vertical mobility patterns.