Organization of the rabbit vitreous body: Lamellae, Cloquet's channel and a novel structure, the 'alae canalis Cloqueti'

Organization of the rabbit vitreous body: Lamellae, Cloquet's channel and a novel structure, the 'alae canalis Cloqueti'
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DOI:
10.1006/exer.1999.0708
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发表时间:
1999-09-01
影响因子:
3.4
通讯作者:
Nieuwenhuis, P
Nieuwenhuis, P
中科院分区:
医学3区
文献类型:
--
作者:
Los, LI;van Luyn, MJA;Nieuwenhuis, P

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尽管兔是研究玻璃体功能和病理生物学的常用动物模型,但关于兔玻璃体结构组织的数据很少。本研究的目的是对兔玻璃体结构进行详细描述,为研究病理生理过程中玻璃体组织的变化提供依据。用补充解剖学方法、光学显微镜和透射电子显微镜对成年兔眼玻璃体进行了研究。观察到玻璃体基质组织的区域性和局部性差异。在区域上,区分了皮质、中间区和中心。此外,局部观察到了特定的结构。片层以漏斗状图案穿过中间区域,汇聚在不对称定位的视盘上。所有眼均有中央通道(Cloquet‘s通道)。我们展示了一种新的结构,附着在Cloquet的通道和髓射线上。由于其翼状、片状的形态,我们将其命名为Alae Canalis Cloqueti。(C)1999年学术出版社。
Even though the rabbit is a frequently used animal model for studies on Vitreous function and pathobiology, data on the structural organization of the rabbit Vitreous are scarce. The aim of the present study is to give a detailed description of rabbit vitreous structure in order to provide a basis for studies on changes in vitreous organization induced by pathophysiological processes. We studied the vitreous body of adult rabbit eyes by complementary anatomical evaluation methods, by light microscopy and by transmission electron microscopy. Regional and local variations in vitreous matrix organization were observed. Regionally, a cortex, an intermediate area, and a centre were distinguished. In addition, specific structures were locally observed. Lamellae run through the intermediate area in a funnel-like pattern, converging upon the asymmetrically positioned optic disc. A central channel (Cloquet's channel) was found in all eyes. We demonstrated a novel structure, attached to Cloquet's channel and to the medullary rays. Because of its wing-shaped sheet-like morphology, we named it the 'alae canalis Cloqueti'. (C) 1999 Academic Press.