Novel fast semi-automated software to segment cartilage for knee MR acquisitions
Novel fast semi-automated software to segment cartilage for knee MR acquisitions
复制标题
DOI：
10.1016/j.joca.2006.11.002
复制
发表时间：
2007-05-01
影响因子：
7
通讯作者：
Lang, P.
中科院分区：
文献类型：
--
作者：
Duryea, J.;Neumann, G.;Lang, P.
目的：验证一种新的快速软件技术，以分割膝关节磁共振（MR）采集的软骨。膝关节骨关节炎（OA）的大型研究将需要快速和可重复的方法来量化膝关节MR数据的软骨变化。在这份报告中，我们的文件和测量的再现性和读者的时间的软件为基础的技术，以量化的体积和厚度的关节软骨对膝关节MR images.Methods：该软件进行了测试，一组重复矢状面三维（3D）双回波稳态（DESS）收购15（8 OA，7正常）科目。独立测量软骨体积（VC）和厚度（ThC）的重新定位、读片员间和读片员内的再现性以及每个软骨板的读片时间。以变异的均方根系数（RMSCoV）为度量标准，定量VC和平均ThC的重现性。VC = 2.0%和ThC = 1.2%（股骨），VC = 2.9%和ThC = 1.6%胫骨平台外侧VC = 5.5%，ThC = 2.4%;髌骨VC = 4.6%，ThC = 2.3%。读数员间重现性的RMSCoV值较高（VC：2.5-8.6%）（ThC：1.9-5.2%），读数员内重现性的RMSCoV值较低（VC：1.6-2.5%）（ThC：1.2-1.9%）。该方法需要平均75.4 min per knee.Conclusions：我们已经记录了一个快速可重复的半自动软件方法来分割膝关节MR采集关节软骨。(C)2006年国际骨关节炎研究学会。由爱思唯尔有限公司出版。保留所有权利。
Objective: Validation of a new fast software technique to segment the cartilage on knee magnetic resonance (MR) acquisitions. Large studies of knee osteoarthritis (OA) will require fast and reproducible methods to quantify cartilage changes for knee MR data. In this report we document and measure the reproducibility and reader time of a software-based technique to quantify the Volume and thickness of articular cartilage on knee MR images.Methods: The software was tested on a set of duplicate sagittal three-dimensional (3D) dual echo steady state (DESS) acquisitions from 15 (8 OA, 7 normal) subjects. The repositioning, inter-reader, and intra-reader reproducibility of the cartilage volume (VC) and thickness (ThC) were measured independently as well as the reader time for each cartilage plate. The root-mean square coefficient of variation (RMSCoV) was used as metric to quantify the reproducibility of VC and mean ThC.Results: The repositioning RMSCoV was as follows: VC = 2.0% and ThC = 1.2% (femur), VC = 2.9% and ThC = 1.6% (medial tibial plateau), VC = 5.5% and ThC = 2.4% (lateral tibial plateau), and VC = 4.6% and ThC = 2.3% (patella). RMSCoV values were higher for the inter-reader reproducibility (VC: 2.5-8.6%) (ThC: 1.9-5.2%) and lower for the intra-reader reproducibility (VC: 1.6-2.5%) (ThC: 1.2-1.9%). T he method required an average of 75.4 min per knee.Conclusions: We have documented a fast reproducible semi-automated software method to segment articular cartilage on knee MR acquisitions. (C) 2006 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved.