EARLY NEUROGENESIS IN WILD-TYPE DROSOPHILA-MELANOGASTER
EARLY NEUROGENESIS IN WILD-TYPE DROSOPHILA-MELANOGASTER
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DOI：
10.1007/bf00848159
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发表时间：
1984-01-01
期刊：
影响因子：
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通讯作者：
CAMPOSORTEGA, JA
中科院分区：
文献类型：
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作者：
HARTENSTEIN, V;CAMPOSORTEGA, JA
果蝇早期神经发生的形态学方面，特别是与神经母细胞从外胚层的神经原性区域的分离和由这些细胞内的生殖带和prophalic叶形成的模式进行了讨论。神经源性外胚层含有神经前体与表皮前体混合，从中线向上延伸到气管树的原基，沿着胚带和侧背在原叶中。胚带成神经细胞根据特征性的空间和时间模式在几个小时的时间内从神经源性外胚层分离。在分离过程的前1/2阶段，发现不同动物的胚带神经母细胞在空间排列和细胞数量上是相同的;这允许识别来自不同胚胎的单个神经母细胞。在后来的发展中遇到了一些困难，这排除了准确描述的神经母细胞模式。的神经发生区的宪法进行了讨论，在有关的突变体影响神经发生的表型。
Morphological aspects of early neurogenesis in Drosophila, in particular with the segregation of neuroblasts from the neurogenic region of the ectoderm and the pattern formed by those cells within both the germ band and the procephalic lobe are discussed. The neurogenic ectoderm contains neural precursors intermingled with epidermal precursors, extending from the midline up to the primordia of the tracheal tree along the germ band and laterodorsally in the procephalic lobe. Germ band neuroblasts segregate from the neurogenic ectoderm during a period of several hours according to characteristic spatial and temporal patterns. During the 1st 1/2 of the segregation process the pattern of germ band neuroblasts was found to be the same in different animals in spatial arrangement and number of cells; this permitted the identification of individual neuroblasts from different embryos. Later in development several difficulties were encountered which precluded an exact description of the neuroblast pattern. The constitution of the neurogenic region is discussed in relation to the phenotype of mutants affecting neurogenesis.