Quantitative Procedures in 3D PET

Quantitative Procedures in 3D PET
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DOI:
10.1007/978-94-017-3475-2_3
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发表时间:
1998
期刊:
--
影响因子:
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通讯作者:
D. Bailey
D. Bailey
中科院分区:
其他
文献类型:
--
作者:
D. Bailey

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正电子断层扫描一直有很强的定量重点。在良好控制的校准条件下,2D采集产生的重建体积提供精确到百分之几的放射性浓度。这主要是由于散射符合的接受度低以及随机符合、死区时间和衰减的校正精度。然而,在3D PET中,这些因素中的许多因素被3D重建所需的采集几何结构和程序改变。本章讨论了目前采用的方法,以应用定量3D PET所需的各种校正。
Positron tomography has always had a strong quantitative emphasis. The reconstructed volumes which result from 2D acquisition provide radioactivity concentrations accurate to within a few percent under well-controlled, calibrated conditions. This is mostly due to the low acceptance of scattered coincidences and the accuracy of the corrections for random coincidences, dead time, and attenuation. In 3D PET though, many of these factors are altered by the acquisition geometry and the procedures needed for 3D reconstruction. This chapter discusses the approaches taken at present to applying the various corrections needed for quantitative 3D PET.