METABOLISM OF INORGANIC ARSENIC (AS-74) IN HUMANS FOLLOWING ORAL INGESTION
METABOLISM OF INORGANIC ARSENIC (AS-74) IN HUMANS FOLLOWING ORAL INGESTION
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DOI：
10.1016/0041-008x(79)90157-1
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发表时间：
1979-01-01
影响因子：
3.8
通讯作者：
SANDI, E
中科院分区：
文献类型：
--
作者：
TAM, GKH;CHARBONNEAU, SM;SANDI, E
口服剂量的无载体74 As（约6 μ Ci/人; 0.01μ g As/人）[一种潜在的致癌物质]作为砷酸给药于6名成年男性。在给药后的前5天内，一些[58%]的74 As剂量经尿液排泄。尿中砷的化学形态比例为：二甲基胂酸51%，一甲基砷化合物21%，无机砷27%。
Oral doses of carrier-free 74As (.simeq. 6 .mu.Ci/man; .simeq. 0.01 .mu.g As/man) [a potential carcinogen] as arsenic acid were administered to 6 adult males. Some [58%] of the 74As dose was excreted in the urine in the first 5 days after dosing. The proportion of chemical species of arsenic in the urine was as follows: 51% dimethylarsinic acid, 21% monomethylarsenic compound and 27% inorganic As.