In pursuit of taste phenotypes.
In pursuit of taste phenotypes.
复制标题
追求味觉表型。
DOI：
10.1093/chemse/bjt007
复制
发表时间：
2013
期刊：
影响因子：
3.5
通讯作者：
Green,BarryG
中科院分区：
文献类型：
--
作者：
Green,BarryG
Notable progress has been made relating individual differences in bitter taste sensitivity to specific alleles and TAS2R receptors, but psychophysical evidence of reliable phenotypes for other tastes has been more elusive. In this issue, Wise and Breslin report a study of individual differences in threshold sensitivity to sour and salty taste, which, though failing to find clear phenotypes, exemplifies the type of approach and analysis necessary to disentangle sources of variance inherent in the psychophysical measures applied from those attributable to true differences in sensitivity. Methodological and theoretical lessons that can be taken from this work are discussed in the context of the early and dramatic evidence of chemosensory phenotypes that belied the complexity of taste receptor genetics and focused attention solely on peripheral determinants of sensitivity.
