COMPRESSIVE PROPERTIES OF CORTICAL BONE - MINERAL ORGANIC INTERFACIAL BONDING
COMPRESSIVE PROPERTIES OF CORTICAL BONE - MINERAL ORGANIC INTERFACIAL BONDING
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DOI：
10.1016/0142-9612(94)90263-1
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发表时间：
1994-01-01
期刊：
影响因子：
14
通讯作者：
GUZELSU, N
中科院分区：
文献类型：
--
作者：
WALSH, WR;GUZELSU, N
骨组织是一种各向异性非均质复合材料，由嵌入有机基质（I 型胶原蛋白和非胶原蛋白）中的无机骨矿物纤维（羟基磷灰石）组成。影响整体机械行为的因素包括成分体积分数、机械性能、取向和界面键合相互作用。矿物和有机成分之间的界面结合部分基于带负电的有机域和带正电的矿物表面之间的静电相互作用。磷酸盐和氟离子已被证明可以改变矿物-有机相互作用，从而影响骨在张力下的机械性能。本研究探讨了磷酸盐和氟离子对皮质骨压缩特性的影响。
Bone tissue is an anisotropic non-homogeneous composite material composed of inorganic, bone mineral fibres (hydroxyapatite) embedded in an organic matrix (type I collagen and non-collagenous proteins). Factors contributing to the overall mechanical behaviour include constituent volume fraction, mechanical properties, orientation and interfacial bonding interactions. Interfacial bonding between the mineral and organic constituents is based, in part, on electrostatic interactions between negatively charged organic domains and the positively charged mineral surface. Phosphate and fluoride ions have been demonstrated to alter mineral-organic interactions, thereby influencing the mechanical properties of bone in tension. The present study explores the effects of phosphate and fluoride ions on the compressive properties of cortical bone.