A Versatile Approach to β-Amyloid Fibril-Binding Compounds Exploiting the Shirakawa/Hayashi Protocol for trans-Alkene Synthesis
A Versatile Approach to β-Amyloid Fibril-Binding Compounds Exploiting the Shirakawa/Hayashi Protocol for trans-Alkene Synthesis
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DOI：
10.1021/ol8029593
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发表时间：
2009-02-19
期刊：
影响因子：
5.2
通讯作者：
Skrydstrup, Troels
中科院分区：
文献类型：
--
作者：
Huynh, Tri H. V.;Mantel, Mette Louise H.;Skrydstrup, Troels
Application of the Sonogashira coupling reaction followed by a trans-selective alkyne reduction proved highly adaptable for the efficient synthesis of a class of beta-amyloid fibril binding compounds possessing a styrylbenzene motif such as FSB, an FSB dimer, and F-19-BAY94-9172.
