A tomato cysteine protease required for Cf-2-dependent disease resistance and suppression of autonecrosis
A tomato cysteine protease required for Cf-2-dependent disease resistance and suppression of autonecrosis
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DOI：
10.1126/science.1069288
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发表时间：
2002-04-26
期刊：
影响因子：
56.9
通讯作者：
Jones, JDG
中科院分区：
文献类型：
--
作者：
Krüger, J;Thomas, CM;Jones, JDG
植物抗病（R）蛋白如何识别病原体并激活植物防御，目前知之甚少。Rcr 3是Cf-2的功能所特别需要的，Cf-2是一个培育到栽培番茄（Lycopersicon esculentum）中以抵抗叶霉病的Lycopersicon pimpinellifolium基因。rcr 3编码一种分泌型木瓜蛋白酶样半胱氨酸内切蛋白酶。遗传分析表明Rcr 3与L. pimpinellifolium Ne基因抑制由其L. esculentum等位基因，ne（坏死）。Rcr 3等位基因从这两个物种编码的蛋白质，不同的只有7个氨基酸，Rcr 3在Cf-2依赖的防御和自坏死的可能作用进行了讨论。
Little is known of how plant disease resistance (R) proteins recognize pathogens and activate plant defenses. Rcr3 is specifically required for the function of Cf-2, a Lycopersicon pimpinellifolium gene bred into cultivated tomato (Lycopersicon esculentum) for resistance to Cladosporium fulvum. Rcr3 encodes a secreted papain-like cysteine endoprotease. Genetic analysis shows Rcr3 is allelic to the L. pimpinellifolium Ne gene, which suppresses the Cf-2-dependent autonecrosis conditioned by its L. esculentum allele, ne (necrosis). Rcr3 alleles from these two species encode proteins that differ by only seven amino acids, Possible roles of Rcr3 in Cf-2-dependent defense and autonecrosis are discussed.