On the Mechanism for Flow in the Efferent Ducts

On the Mechanism for Flow in the Efferent Ducts
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DOI:
10.1002/j.1939-4640.1980.tb00046.x
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发表时间:
1980-11
影响因子:
--
通讯作者:
H. Winet
H. Winet
中科院分区:
--
文献类型:
--
作者:
H. Winet

文献摘要

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提出了一种用于泵送传出管(ED)内容物的纤毛蠕动模型,该模型可以预测观察到的体积流量,并且与附睾的正压力梯度一致。该模型预测流体流动的主要贡献者是蠕动成分。相反,纤毛可以通过产生回流来减少流量。随着液体粘度的增加,这种效应可能会大大降低,而液体粘度又是精子浓度的函数。从这项研究得出的结论是,如果蠕动波有33%或更多的收缩,则ED中的精子浓度至少为4×108细胞cm−3,并且ED中的流速与睾丸网中的流速相同;然后在 ED 中的传输是由于纤毛蠕动泵送。
A cilio-peristaltic model for pumping of efferent duct (ED) contents that predicts the observed volumetric flow rates and is consistent with a positive pressure gradient toward the epididymis is proposed. The model predicts that the major contributor to fluid flow is the peristaltic component. The cilia, in contrast, may reduce flow by creating reflux. This effect may be reduced considerably with an increase in fluid viscosity, which is in turn a function of sperm concentration. It is concluded from this investigation that if the peristaltic wave has a 33% or more constriction, the spermatozoan concentration in the ED is at least 4 × 108 cells cm−3 and flow rates in the ED are the same as in the rete testis; then transit in the ED is due to cilio-peristaltic pumping.