Surface plasmon biosensor based on Bi2Te3 antimonene heterostructure for the detection of cancer cells.
Surface plasmon biosensor based on Bi2Te3 antimonene heterostructure for the detection of cancer cells.
复制标题
基于Bi2Te3锑烯异质结构的表面等离子体生物传感器用于检测癌细胞。
DOI：
10.1364/ao.454789
复制
发表时间：
2022
期刊：
影响因子：
1.9
通讯作者：
Y. Singh
中科院分区：
文献类型：
--
作者：
Arun Uniyal;Brajlata Chauhan;A. Pal;Y. Singh
这项理论研究提出了使用基于棱镜的表面等离子体共振生物传感器对癌细胞进行初步检测。表面等离子体共振(SPR)生物传感器无需标记，快速，支持实时研究，包括更高的灵敏度，它在检测不同形式的癌症方面具有巨大的可能性。癌细胞的折射率变化在1.360-1.401之间。对SPR传感器的性能进行了分析。分析了皮肤、宫颈、血液、肾上腺和乳房的不同类型的癌细胞(I型和II型)，分别获得了292、384、229、242、254和261(度/RIU)的敏感性。HeLa细胞的优值系数达到115.2RIU-1，基底细胞的检测精度达到0.32deg-1。
This theoretical investigation proposes the preliminary stage detection of cancer cells using a prism-based surface plasmon resonance biosensor. The surface plasmon resonance (SPR) biosensor is label-free and rapid; it supports real-time investigations, including greater sensitivity, and it has an enormous possibility for detecting different forms of cancer. The refractive index alteration of cancer cells is 1.360-1.401. The performance of the SPR sensor has been analyzed. The different types of cancer cells for skin, cervical, blood, adrenal, and breast (type I and II) have been analyzed, and sensitivities of 292, 384, 229, 242, 254, and 261 (degree/RIU) have been achieved, respectively. A high figure of merit of 115.2RIU-1 has been achieved for HeLa cells and achieved detection accuracy of 0.32deg-1 for basal cells.