Dorsal root ganglion pulsed radiofrequency for the management of intractable vertebral metastatic pain: a case series.
Dorsal root ganglion pulsed radiofrequency for the management of intractable vertebral metastatic pain: a case series.
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DOI：
10.1111/pme.12629
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发表时间：
2015-05
期刊：
影响因子：
3.1
通讯作者：
Y. Arai;Makoto Nishihara;Yoshihiro Yamamoto;M. Arakawa;Miki Kondo;C. Suzuki;Akiko Kinoshita;Kazuyo Kambara;T. Ikemoto
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文献类型：
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作者：
Y. Arai;Makoto Nishihara;Yoshihiro Yamamoto;M. Arakawa;Miki Kondo;C. Suzuki;Akiko Kinoshita;Kazuyo Kambara;T. Ikemoto
目的转移性骨痛是癌痛的特征性疼痛，是一种难治性癌痛，既包括伤害性疼痛，也包括神经性疼痛。虽然一些药物对疼痛性骨转移的管理是有效的，但移动时的疼痛是最难治的疼痛形式之一。尽管脉冲射频（RF）显著降低了神经性疼痛、慢性疼痛和脊椎转移性疼痛，但这些研究中报告的病例数量非常少（5例或更少）。设计案例报告。设置单一疼痛中心。患者15例患有顽固性脊椎转移性疼痛的患者。干预背根神经节（DRG）脉冲射频。观察指标：静息和活动时疼痛的数字评定量表（NRS）。结果脉冲射频治疗后，几乎所有患者的疼痛均得到了明显缓解。未报告严重副作用。结论DRG脉冲射频治疗顽固性脊椎转移瘤疼痛疗效满意。转移性骨痛是癌症疼痛的特征，并且是难治性癌症疼痛的一种形式，因为疼痛不仅包括伤害性疼痛，而且包括神经性疼痛。虽然一些药物对疼痛性骨转移的管理是有效的，但移动时的疼痛是最难治的疼痛形式之一。DRG脉冲射频治疗对顽固性椎体转移性疼痛患者提供了良好的止痛效果。
OBJECTIVE Metastatic bone pain is characteristic of cancer pain and is a form of refractory cancer pain, as the pain includes not only nociceptive but also neuropathic pain. Although some drugs are effective in the management of painful bone metastases, pain while moving is one of the most refractory forms of pain. Although pulsed radiofrequency (RF) dramatically reduces neuropathic pain, chronic pain, and vertebral metastatic pain, the number of cases reported in these studies was very small (five or less). DESIGN Case report. SETTING Single pain center. PATIENTS Fifteen patients suffering from intractable vertebral metastatic pain. INTERVENTIONS Dorsal root ganglion (DRG) pulsed RF. OUTCOME MEASURES A numerical rating scale (NRS) of pain at rest and while moving. RESULTS Almost all patients experienced sound pain relief after the pulsed RF treatment. There were no severe side effects reported. CONCLUSION DRG pulsed RF procedure provided sound pain relief for patients with intractable vertebral metastatic pain. Metastatic bone pain is characteristic of cancer pain and is a form of refractory cancer pain, as the pain includes not only nociceptive but also neuropathic pain. Although some drugs are effective in the management of painful bone metastases, pain while moving is one of the most refractory forms of pain. DRG pulsed RF procedure provided sound pain relief for patients with intractable vertebral metastatic pain.