Outcomes and predictors of failure of thrombolysis for iliofemoral deep venous thrombosis
Outcomes and predictors of failure of thrombolysis for iliofemoral deep venous thrombosis
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DOI：
10.1016/j.jvsv.2014.07.007
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发表时间：
2015-01-01
影响因子：
3.2
通讯作者：
Chaer, Rabih A.
中科院分区：
文献类型：
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作者：
Avgerinos, Efthymios D.;Hager, Eric S.;Chaer, Rabih A.
背景资料：据报道，导管直接溶栓（CDT）与连续的机械技术，当成功的，以减轻急性髂股深静脉血栓形成（IFDVT）的症状，并降低血栓后综合征（PTS）的发生率。本研究的目的是确定长期的结果，导管为基础的干预IFDVT，并确定预测的即时和中长期的失败，将指导最佳patient selection.Methods：从一个前瞻性维护的数据库中确定了2007年5月至2013年3月期间接受CDT或药物机械溶栓IFDVT的患者。根据血栓溶解程度（50%）和DVT 30天复发评估围手术期即刻失败的预测因素。通过溶解节段的超声成像和Villalta评分（>= 5 vs.
Background: Catheter-directed thrombolysis (CDT) with adjunctive mechanical techniques, when successful, is reported to alleviate symptoms of acute iliofemoral deep venous thrombosis (IFDVT) and to lower the occurrence of the post thrombotic syndrome (PTS). This study aimed to determine longer term outcomes of catheter-based interventions for IFDVT and to identify predictors of immediate and mid-long-term failures that would guide optimal patient selection.Methods: Consecutive patients who underwent CDT or pharmacomechanical thrombolysis for IFDVT between May 2007 and March 2013 were identified from a prospectively maintained database. Assessment of predictors of immediate periprocedural failure was based on the degree of clot lysis (50%) and 30-day recurrence of DVT. Long-term anatomic and clinical failures and outcomes were assessed by ultrasound imaging of the lysed segments and Villalta score (>= 5 vs