Programmable self-assembly of metal ions inside artificial DNA duplexes
Programmable self-assembly of metal ions inside artificial DNA duplexes
复制标题
DOI：
10.1038/nnano.2006.141
复制
发表时间：
2006-12-01
影响因子：
38.3
通讯作者：
Carell, Thomas
中科院分区：
文献类型：
--
作者：
Tanaka, Kentaro;Clever, Guido H.;Carell, Thomas
构建功能性纳米系统的终极自底向上方法需要原子和分子在三维空间的精确排列。DNA是目前最突出的分子之一，能够自组装成复杂的网络（1,2），因此被认为是“纳米世界的硅”(3)。相反，金属和金属离子是这些材料中建立诸如导电性或磁性等功能所必需的原子构件。在这里，我们报道了一个新的概念，有效地结合金属离子和DNA。利用DNA结构作为基质，在精确控制金属离子的元素、数量和组成的情况下，对不同金属离子的络合进行稳健编程。
The ultimate bottom-up approach for the construction of functional nanosystems requires the precise arrangement of atoms and molecules in three dimensions. DNA is currently one of the most prominent molecules able to self-assemble into complex networks(1,2) and is therefore regarded as the 'silicon of the nano-world'(3). Metals and metal ions, in contrast, are the atomic building-blocks needed in such materials to establish functions such as electrical conductivity or magnetism. Here we report a new concept, which efficiently combines metal ions and DNA. The DNA structure is used as a matrix to program robustly the complexation of different metal ions under precise control with regard to element, number and composition.