RHOMBUS DEFORMATION OF RETINAL LATERAL DISPLACEMENT AFTER EPIRETINAL MEMBRANE REMOVAL REVEALED BY DIFFEOMORPHIC IMAGE REGISTRATION
RHOMBUS DEFORMATION OF RETINAL LATERAL DISPLACEMENT AFTER EPIRETINAL MEMBRANE REMOVAL REVEALED BY DIFFEOMORPHIC IMAGE REGISTRATION
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DOI：
10.1097/iae.0000000000003775
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发表时间：
2023-07-01
影响因子：
3.3
通讯作者：
Nakano，Tadashi
中科院分区：
文献类型：
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作者：
Honzawa，Koki;Horiguchi，Hiroshi;Nakano，Tadashi
目的：建立一种基于图像配准的分析方法，评价视网膜前膜（epiretinalmembrane，ERM）切除后微血管移位情况。术后的光学相干断层扫描血管造影（OCTA）图像转换为相应的术前图像根据配置算法，使用numeromorphism。测量的中心凹无血管区（FAZ）面积的变化与中心凹厚度（CFT）呈显着负相关。每个像素计算的微血管位移平均幅度在鼻区为69±27 µm，相对小于其他区域。包括微血管位移幅度和位移矢量的矢量图显示了17只眼睛的独特矢量流模式，称为菱形变形征。眼睛与此变形的迹象表明，手术引起的变化，在FAZ地区和CFT和温和的ERM阶段比那些没有这个sign.Conclusion：作者计算和可视化微血管位移使用的双态性。作者发现了一种独特的模式（菱形变形）的视网膜侧向位移通过ERM删除，这是显着相关的严重程度的ERM。
Purpose:To establish an analysis method using diffeomorphic image registration and evaluate microvascular displacement through epiretinal membrane (ERM) removal.Methods:Medical records of eyes that underwent vitreous surgery for ERM were reviewed. Postoperative optical coherence tomography angiography (OCTA) images were converted to the corresponding preoperative images according to a configured algorithm using diffeomorphism.Results:Thirty-seven eyes with ERM were examined. Measured changes in the foveal avascular zone (FAZ) area showed a significant negative correlation with central foveal thickness (CFT). The average amplitude of microvascular displacement calculated for each pixel was 69±27 µm in the nasal area, which was relatively smaller than that in other areas. The vector map, which included both the amplitude and the vector of microvasculature displacement, showed a unique vector flow pattern called the rhombus deformation sign in 17 eyes. Eyes with this deformation sign showed less surgery-induced changes in the FAZ area and CFT and a milder ERM stage than those without this sign.Conclusion:The authors calculated and visualized microvascular displacement using diffeomorphism. The authors found a unique pattern (rhombus deformation) of retinal lateral displacement through ERM removal, which was significantly associated with the severity of ERM.