Continuous chemoselective methylation of m-cresol and phenol with supercritical methanol over solid acid and base metal oxide catalysts
Continuous chemoselective methylation of m-cresol and phenol with supercritical methanol over solid acid and base metal oxide catalysts
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DOI：
10.1002/adsc.200505191
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发表时间：
2005-10-01
影响因子：
5.4
通讯作者：
Ikariya, T
中科院分区：
文献类型：
--
作者：
Oku, T;Arita, Y;Ikariya, T
在连续流动固定床反应器中，研究了金属氧化物催化剂(氧化镁、氧化锆、铯-磷-硅和铁钒/二氧化硅)催化间甲酚和苯酚与超临界甲醇(SCCH(3)OH)的化学选择性甲基化反应。使用SCCH(3)OH作为载体，与气相反应相比，产物的选择性有了显著的变化，并显著抑制了CH3OH在反应过程中的降解，从而提高了催化剂的寿命。超临界条件下考察的固体催化剂的酸碱性质对反应的化学选择性有很大影响。
The chemoselective methylation of m-cresol and phenol with supercritical methanol (scCH(3)OH) promoted by metal oxide catalysts (MgO, ZrO2, Cs-P-Si and Fe-V/SiO2) was investigated in a continuous flow fixed bed reactor. The use of scCH(3)OH as a carrier medium led to a significant change in the product selectivity compared to that attained in the gas phase reaction, and caused a marked suppression of the degradation of CH3OH during the reaction, resulting in an improvement in the catalyst lifetime. The chemoselective outcome of the reaction was highly influenced by the acid-base character on the solid catalysts examined under supercritical conditions.