Incompatibility between amphibian hosts and xenoplastic grafts as related to host age

Incompatibility between amphibian hosts and xenoplastic grafts as related to host age
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两栖动物宿主和异种移植物之间的不相容性与宿主年龄有关

DOI:
10.1002/jez.1400980104
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发表时间:
1945
影响因子:
--
通讯作者:
M. Harris
M. Harris
中科院分区:
--
文献类型:
--
作者:
R. M. Eakin;M. Harris

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Bytinski-Salz('29 a),以及许多其他人。不仅在近缘物种之间的异种移植成功,而且在有尾目动物和无尾目动物胚胎之间的衰老性移植也经常成功。由于这些研究的目的主要是胚胎学,因此仅对宿主的体液和细胞反应以及移植物的最终命运进行了单独观察。这几项研究所提供的重要事实可以概括如下:众所周知,在许多情况下,有尾目和无尾目之间的胚胎移植失败是由于存在直接损害异种移植物的有毒物质。例如,Bytinski-Salz('29 b)、Cotronei和Perri(' 34)和其他人已经表明,胚胎移植或某些无尾类动物(如棕背蟾蜍或蟾蜍)的提取物会杀死有尾目动物的胚胎,从而排除了衰老性移植。另一方面,这些毒性因子在早期胚胎中是轻微的或不存在的形式,如Bombinator igneus和Hyla arborea; urodele植入物在这里不仅可以持续,但经历分化和生长。
Bytinski-Salz ('29a), and many others. Not only has heteroplastic transplantation between closely related species been successful, but often also senoplastic transplantation, as between urodele and anuran embryos. Since the objectives of these studies were primarily embryological, only isolated observations were made on the humoral and cellular responses of the host and the ultimate fate of the graft. The important facts which these few studies have provided ma:-be summarized as follows.It is known that embryonic grafts between urodeles and anurans fail in many instances owing to the presence of toxic substances which directly damage the alien grafts. Bytinski-Salz ('29b), Cotronei and Perri ('34), and others have shown, for example, that embryonic grafts or extracts from certain anurans such as Pelobates fuscus or Bufo viridis will kill urodele embryos, thus precluding senoplastic transplantations. On the other hand, these toxic factors are slight or absent in early embryos of forms such as Bombinator igneus and Hyla arborea; urodele implants here may not only persist but undergo differentiation and growth.