Effect of Iyengar yoga practice on fatigue and diurnal salivary cortisol concentration in breast cancer survivors
Effect of Iyengar yoga practice on fatigue and diurnal salivary cortisol concentration in breast cancer survivors
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DOI：
10.1111/j.1745-7599.2010.00573.x
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发表时间：
2011-03-01
影响因子：
--
通讯作者：
Bendel, Robert
中科院分区：
文献类型：
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作者：
Banasik, Jacquelyn;Williams, Holly;Bendel, Robert
目的：研究定期艾扬格瑜伽练习对II-IV期乳腺癌幸存者（n = 18）自我感知的心理社会功能和昼夜唾液皮质醇分泌的影响。数据来源：妇女被随机分配参加瑜伽练习，每周两次，每次90分钟，持续8周（n = 9）或等待名单，非干预性对照组（n = 9）。传统的艾扬格瑜伽套路，随着参与者获得力量和灵活性，难度逐渐增加。在基线和8周的研究期后，妇女完成自我报告工具，以记录心理社会和身体功能的各个方面，并收集唾液样本进行皮质醇分析，每天四次，连续两天。结论：瑜伽组有较低的早晨和下午5时唾液皮质醇和改善情绪健康和疲劳评分。乳腺癌幸存者有慢性心理社会困扰的风险，这可能会改变下丘脑-垂体-肾上腺轴的活动，导致皮质醇分泌的异常调节，增加免疫功能障碍和癌症进展的风险。定期练习瑜伽可能是一种低风险，具有成本效益的方法，可以改善乳腺癌幸存者的心理社会功能，疲劳和皮质醇分泌调节。这些发现需要更大规模的随机研究进行验证。
Purpose: To examine the effect of regular Iyengar yoga practice on measures of self-perceived psychosocial function and diurnal salivary cortisol secretion in stage II-IV breast cancer survivors (n = 18).Data sources: Women were randomly assigned to attend yoga practice for 90 min twice weekly for 8 weeks (n = 9) or to a wait-listed, noninterventional control group (n = 9). Traditional Iyengar yoga routines that progressively increased in difficulty as participants gained strength and flexibility were used. At baseline and after the 8-week study period, women completed self-report instruments to document various aspects of psychosocial and physical functioning, and collected salivary samples for cortisol analysis four times during the day for two consecutive days.Conclusions: The yoga group had lower morning and 5 p.m. salivary cortisol and improved emotional well-being and fatigue scores.Implications for practice: Breast cancer survivors are at risk for chronic psychosocial distress that may alter activity of the hypothalamic-pituitary-adrenal axis, resulting in aberrant regulation of cortisol secretion and increased risk of immune dysfunction and cancer progression. Regular yoga practice may be a low-risk, cost-effective way to improve psychosocial functioning, fatigue, and regulation of cortisol secretion in breast cancer survivors. These findings require validation with a larger randomized study.