Fine Subdivisions of the Semantic Network Supporting Social and Sensory-Motor Semantic Processing
Fine Subdivisions of the Semantic Network Supporting Social and Sensory-Motor Semantic Processing
复制标题
支持社会和感觉运动语义处理的语义网络的精细细分
DOI：
10.1093/cercor/bhx148
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发表时间：
2018-08-01
期刊：
影响因子：
3.7
通讯作者：
Li, Xingshan
中科院分区：
文献类型：
--
作者：
Lin, Nan;Wang, Xiaoying;Li, Xingshan
神经影像学研究一致表明，语义处理涉及一个由分布在额叶、顶叶和颞叶的多模态皮层区域组成的大脑网络。然而，很少有人知道语义信息是如何在网络中组织和处理。最近的一些研究表明，感觉运动语义信息调制这个网络的激活。其他研究表明，这个网络对社会语义信息的反应比对其他信息的反应更大。使用功能磁共振成像，我们集体调查的大脑激活诱发的社会和感觉运动语义信息操纵的社会性和想象力的动词在一个词的理解任务。我们在网络中检测到两个亚组的大脑区域，分别显示出社会性和意象性效应。这两个亚群的区域是不同的，但在双侧角回和相邻的颞中回重叠。对静息态功能连接的随访分析表明，2个亚组区域的分离部分与其内在功能连接差异相关。此外，在左前颞叶观察到社交性和想象性的交互作用。我们的研究结果表明，多模式皮质语义网络具有处理和整合社交和感觉运动语义信息的精细细分。
Neuroimaging studies have consistently indicated that semantic processing involves a brain network consisting of multimodal cortical regions distributed in the frontal, parietal, and temporal lobes. However, little is known about how semantic information is organized and processed within the network. Some recent studies have indicated that sensorymotor semantic information modulates the activation of this network. Other studies have indicated that this network responds more to social semantic information than to other information. Using fMRI, we collectively investigated the brain activations evoked by social and sensory-motor semantic information by manipulating the sociality and imageability of verbs in a word comprehension task. We detected 2 subgroups of brain regions within the network showing sociality and imageability effects, respectively. The 2 subgroups of regions are distinct but overlap in bilateral angular gyri and adjacent middle temporal gyri. A follow-up analysis of resting-state functional connectivity showed that dissociation of the 2 subgroups of regions is partially associated with their intrinsic functional connectivity differences. Additionally, an interaction effect of sociality and imageability was observed in the left anterior temporal lobe. Our findings indicate that the multimodal cortical semantic network has fine subdivisions that process and integrate social and sensory- motor semantic information.