Comparative analysis of the structural polypeptides of Ebola viruses from Sudan and Zaire.
Comparative analysis of the structural polypeptides of Ebola viruses from Sudan and Zaire.
复制标题
苏丹和扎伊尔埃博拉病毒结构多肽的比较分析。
DOI:
10.1093/infdis/147.2.276
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发表时间:
1983
期刊:
影响因子:
--
通讯作者:
Kiley,MP
中科院分区:
文献类型:
--
作者:
Buchmeier,MJ;DeFries,RU;McCormick,JB;Kiley,MP
Polypeptide structural analyses were performed by tryptic peptide mapping to assess the relationship between isolates of Ebola virus obtained in Sudan and Zaire. The results of these analyses indicate (1) that the Sudan and Zaire isolates are unique viral agents, (2) that multiple isolates within each group bear close resemblance to one another, (3) that suggestive evidence exists of conservation of homologous structure in the VP-2 (virion protein no. 2) nucleocapsid proteins of these viruses, and (4) that protein differences between the two Ebola virus subtypes appear to reside in the VP-l and VP-3 virion polypeptides.