Inhibition of T lymphocyte activation and apoptotic cell death by cyclosporin A and tacrolimus (FK506). Its relevance to therapy of HIV infection.
Inhibition of T lymphocyte activation and apoptotic cell death by cyclosporin A and tacrolimus (FK506). Its relevance to therapy of HIV infection.
复制标题
环孢菌素 A 和他克莫司 (FK506) 抑制 T 淋巴细胞活化和凋亡细胞死亡。
DOI：
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复制
发表时间：
1995
影响因子：
--
通讯作者：
C. Bonham
中科院分区：
文献类型：
--
作者：
A. Thomson;C. Bonham
Theoretically, drugs that inhibit programmed cell death could be used to inhibit the increased apoptotic decay of lymphocyte populations in human immunodeficiency virus (HIV) infection. The concept that immunopathologic processes cause immune suppression provides a further rationale for the use of agents such as cyclosporin A (CsA) or tacrolimus (formerly known as FK506) early in HIV infection to reduce cytotoxic CD8+ T cell-mediated destruction of HIV-infected target cells.
DOI：
10.1073/pnas.90.4.1411
发表时间：
1993-02-15
影响因子：
11.1
作者：
BELL, KD;RAMILO, O;VITETTA, ES
通讯作者：
VITETTA, ES
胸腺细胞凋亡的调节。
DOI：
--
发表时间：
1993
期刊：
Thymus
影响因子：
--
作者：
Cairns,JS;Mainwaring,MS;Cacchione,RN;Walker,JA;McCarthy,SA
通讯作者：
McCarthy,SA