Bacillus Calmette-Guerin, Mycobacterium bovis, as an immunomodulator in atopic diseases
Bacillus Calmette-Guerin, Mycobacterium bovis, as an immunomodulator in atopic diseases
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DOI：
10.1016/j.iac.2006.02.002
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发表时间：
2006-05-01
影响因子：
2.6
通讯作者：
Akdis, CA
中科院分区：
文献类型：
--
作者：
Barlan, I;Bahceciler, NN;Akdis, CA
从卫生学假说出发，综述了特应性与卡介苗、纯化蛋白衍生物皮试反应、分枝杆菌病及环境分枝杆菌的关系。提到了分枝杆菌物种在通过Toll样受体激活先天免疫应答中的作用。卡介苗作为一种潜在的治疗辅助特应性疾病的影响和前景进行了讨论。
Based on the hygiene hypothesis association between atopy and bacillus Calmette-Guerin (BCG), purified protein derivative skin test reaction, mycobacterial disease, and environmental mycobacteria are summarized. The role of mycobacterial species in the activation of the innate immune response through Toll-like receptors is mentioned. The implications and perspectives of BCG as a potential therapeutic adjuvant in atopic disease are discussed.