Microchip free-flow electrophoresis on glass substrate using laser-printing toner as structural material
Microchip free-flow electrophoresis on glass substrate using laser-printing toner as structural material
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DOI：
10.1002/elps.200600137
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发表时间：
2006-12-01
期刊：
影响因子：
2.9
通讯作者：
do Lago, Claudimir Lucio
中科院分区：
文献类型：
--
作者：
de Jesus, Dosil Pereira;Blanes, Lucas;do Lago, Claudimir Lucio
In this work, a microfluiclic free-flow electrophoresis device, obtained by thermal toner transferring on glass substrate, is presented. A microdevice can be manufactured in only 1 h. The layout of the microdevice was designed in order to improve the fluidic and electrical characteristics. The separation channel is 8 Am deep and presents an internal volume of 1.42 mu L. The deleterious electrolysis effects were overcome by using a system that isolates the electrolysis products from the separation channel. The Joule heating dissipation in the separation channel was found to be very efficient up to a current density of 8.83 mA/mm(2) that corresponds to a power dissipation per unit volume of running electrolyte of 172 mW/mu L. Promising results were obtained in the evaluation of the microdevices for the separation of ionic dyes. The microfluidic device can be used for a continuous sample pretreatment step for micro total analysis system.
