Effects of lifestyle on hepatobiliary enzyme abnormalities following the Fukushima Daiichi nuclear power plant accident: The Fukushima health management survey.
Effects of lifestyle on hepatobiliary enzyme abnormalities following the Fukushima Daiichi nuclear power plant accident: The Fukushima health management survey.
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DOI：
10.1097/md.0000000000012890
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发表时间：
2018-10
期刊：
影响因子：
1.6
通讯作者：
Ohira H
中科院分区：
文献类型：
--
作者：
Takahashi A;Ohira T;Okazaki K;Yasumura S;Sakai A;Maeda M;Yabe H;Hosoya M;Ohtsuru A;Kawasaki Y;Suzuki H;Shimabukuro M;Sugiura Y;Shishido H;Hayashi Y;Nakano H;Kobashi G;Kamiya K;Ohira H
福岛第一核电站事故引起的生活方式的巨大变化增加了肝胆酶异常（HEA）的患病率。我们的目的是评估HEA与特定的生活方式和灾害相关的因素在居民谁住在附近的福岛第一核电站。这项横断面研究包括22，246名居民，他们在2011年6月至2012年3月期间接受了全面健康检查和心理健康和生活方式调查。事故发生后，居民根据居住区域和住房状况分为2组。HEA与生活方式和灾害相关因素（包括心理困扰）之间的关联采用Logistic回归分析进行估计，并对人口统计学和生活方式因素进行调整。27.3%的受试者存在HEA。撤离人员中HEA的患病率显著高于对照组（29.5%比25.7%，P <0.001）。 撤离人员和对照组在各种生活方式特征和创伤后应激障碍的患病率方面存在显着差异。多变量logistic回归分析显示，无论疏散状态如何，年龄、性别、中度至重度饮酒、低/无体力活动与HEA显著相关。工作和失业的变化显着相关HEA的控制和疏散，分别。生活方式和灾害相关因素，但不是心理困扰，与HEA谁住在附近的福岛第一核电站事故的受试者。
Dramatic lifestyle changes due to the Fukushima Daiichi Nuclear Power Plant accident increased the prevalence of hepatobiliary enzyme abnormalities (HEA). We aimed to evaluate associations of HEA with specific lifestyle- and disaster-related factors in residents who lived near the Fukushima Daiichi Nuclear Power Plant. This cross-sectional study included 22,246 residents who underwent a Comprehensive Health Check and the Mental Health and Lifestyle Survey from June 2011 to March 2012. Residents were divided into 2 groups based on residential area and housing status after the accident. Associations between HEA and lifestyle- and disaster-related factors, including psychological distress, were estimated using logistic regression analysis adjusted for demographic and lifestyle factors. HEA was present in 27.3% of subjects. The prevalence of HEA was significantly higher in evacuees than controls (29.5% vs 25.7%, P < .001). There were significant differences in various lifestyle characteristics and the prevalence of post-traumatic stress disorder between evacuees and controls. Multivariable logistic regression analysis showed that age, sex, moderate to heavy drinking, and low/no physical activity were significantly associated with HEA regardless of evacuation status. Changes in jobs and unemployment were significantly associated with HEA in controls and evacuees, respectively. Lifestyle and disaster-related factors, but not psychological distress, were associated with HEA among subjects who lived near the Fukushima Daiichi Nuclear Power Plant accident.