Q-switched double frequency Nd:YAG 532-nm nanosecond laser vs. double frequency Nd:YAG 532-nm picosecond laser for the treatment of solar lentigines in Asians
Q-switched double frequency Nd:YAG 532-nm nanosecond laser vs. double frequency Nd:YAG 532-nm picosecond laser for the treatment of solar lentigines in Asians
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DOI：
10.1007/s10103-018-2560-3
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发表时间：
2018-12-01
影响因子：
2.1
通讯作者：
Triyangkulsri, Korn
中科院分区：
文献类型：
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作者：
Vachiramon, Vasanop;Iamsumang, Wimolsiri;Triyangkulsri, Korn
日光性雀斑是常见的色素性皮损。Q开关激光是有效的治疗选择，但炎症后色素沉着(PIH)在较暗的皮肤中很常见。本研究的目的是比较调Q开关磷酸钛钾(KTP)532 nm纳秒激光和KTP 532 nm皮秒激光治疗亚洲人太阳扁平苔藓的疗效和安全性。研究对象为30名上肢至少有2颗太阳能扁豆的患者。总共30对豆状皮损被随机地用调Q开关KTP 532 nm纳秒激光和KTP 532 nm皮秒激光进行单一治疗。在疗效方面，在基线、6周和12周时对平均亮度评分进行评估。色素清除程度由盲人医生和患者评估。采用视觉模拟量表对患者进行满意度评分。不良事件也被记录下来。28名患者完成了这项研究。与基线相比，两种激光的平均亮度得分均有显著改善(p
Solar lentigines are common pigmentary lesions. Q-switched lasers are effective treatment options but postinflammatory hyperpigmentation (PIH) is common in darker skin. The objective of the study is to compare the efficacy and safety in solar lentigines of Asian skin treated by Q-switched potassium titanyl phosphate (KTP) 532-nm nanosecond laser vs. KTP 532-nm picosecond laser for the treatment of solar lentigines in Asians. Thirty patients with at least 2 solar lentigines on the upper extremities were enrolled. A total of 30 paired lentiginous lesions were randomly treated with a single treatment of either Q-switched KTP 532-nm nanosecond laser vs. KTP 532-nm picosecond laser. In terms of efficacy, mean luminance score was evaluated at baseline, at 6th, and 12th week. Degree of pigment clearance was assessed by a blinded physician and the patients. Satisfaction score was rated by patients using visual analogue scale. Adverse events were also recorded. Twenty-eight patients completed the study. Both lasers showed significant improvement in mean luminance score from baseline (p