Catalytic, Direct Synthesis of Bis(boronate) Compounds
Catalytic, Direct Synthesis of Bis(boronate) Compounds
复制标题
双（硼酸酯）化合物的催化直接合成
DOI：
10.1021/cs300320u
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发表时间：
2012
期刊：
影响因子：
12.9
通讯作者：
J. Takaya
中科院分区：
文献类型：
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作者：
K. Ogawa;T. Sato;S. Matsubara;Y. Okayasu;T. Togashi;T. Watanabe;E. J. Takahashi;K. Midorikawa;M. Aoyama;K. Yamakawa;A. Iwasaki;S. Owada;K. Yamanouchi;T. Ohshima;Y. Otake;T. Hara;T. Tanaka;H. Tanaka;H. Tomizawa;M. Yabashi;T. Ishikawa;馬場萌未・鳥飼浩平・海老根真琴・大石 徹;Hitoshi Miyasaka;辻 康之;片山佳樹;J. Takaya
双（硼酸酯）化合物作为用于复杂分子的简洁合成的多用途结构单元已经吸引了很多关注，因为这些化合物能够在C-B键处形成多个C-C键和官能化。过渡金属催化的不饱和烃与二硼的二硼化反应已被用作合成双（硼酸酯）化合物的直接且高度有用的方法。本文综述了近年来在二硼化反应中的底物通用性、不对称合成和新型金属催化剂的发现等方面的研究进展。此外，还将描述通过顺序单硼化反应获得双（硼酸酯）化合物的另一种方法，从而扩展了双（硼酸酯）化合物的直接合成的多样性。
Bis(boronate) compounds have been attracting much attention as versatile building blocks for concise synthesis of complex molecules because these compounds enable multiple C–C bond formations and functionalizations at the C–B bonds. Transition metal-catalyzed diboration reactions of unsaturated hydrocarbons with diborons have been utilized as a straightforward and highly useful method for the synthesis of bis(boronate) compounds. This perspective article will summarize recent development in substrate generality, asymmetric synthesis, and discovery of new metal catalysts in the diboration chemistry. Moreover, another approach to bis(boronate) compounds via sequential monoborylation reaction will also be described, expanding diversity of the direct synthesis of bis(boronate) compounds.