Social trauma as related to cancer of the breast.
Social trauma as related to cancer of the breast.
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DOI：
10.1038/bjc.1971.87
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发表时间：
1971-12
影响因子：
8.8
通讯作者：
Graham S
中科院分区：
文献类型：
--
作者：
Snell L;Graham S
许多作者，主要是心理生理学领域的作者，认为乳腺癌可能与各种不利的心理状态有关，而这些心理状态又可能与在社会环境中经历不幸有关。其他研究表明，内分泌功能可能是这种疾病的病因。因此，我们希望探讨社会创伤的经历，可能会导致内分泌影响和乳腺癌的发展之间的关系。我们假设，乳腺癌病例比对照组更经常在诊断出乳腺癌之前的5年内在其社会环境中遇到创伤性事件。352例乳腺癌病例和670例对照组的其他类型的癌症和非肿瘤性疾病的器官以外的乳房和生殖器从罗斯韦尔公园纪念研究所进行了采访。比较了受试者及其直系亲属和大家庭在多大程度上发生了死亡、离婚、疾病、经济困难、居住流动性和心烦意乱等生活事件。乳腺癌组与对照组在自身或家庭成员经历的单个事件或累积事件数方面均无差异。可能有不同类型的事件，这里没有研究，这与乳腺癌的发展有关。
A number of writers, primarily in the field of psychophysiology, have suggested that breast cancer may be related to a variety of untoward psychological states and that these may be related in turn to having experienced misfortune in the social milieu. Other research has indicated that endocrine function may figure in the etiology of this disease. For these reasons, we wished to examine the relationship between the experiencing of social trauma which could induce endocrine effect and the development of cancer of the breast. We hypothesized that breast cancer cases, more often than controls, would have encountered traumatic incidents in their social milieu in the 5-year period prior to the diagnosis of their disease. Three hundred and fifty-two breast cancer cases and 670 controls with other types of cancer and non-neoplastic diseases of organs other than the breast and genitalia from Roswell Park Memorial Institute were interviewed. Comparisons were made concerning the extent to which the subjects and their immediate and extended families incurred such life events as death, divorce, illness, economic want, residential mobility, and feelings of being upset. No difference was found between the breast cancer cases and the controls either in the experiencing of single events or cumulative numbers of events by themselves or by members of their families. There may be events of a different type, not studied here, which are related to the development of cancer of the breast.