A Brief Report on Outcomes of Stereotactic Ablative Radiotherapy for a Second Primary Lung Cancer: Evidence in Support of Routine CT Surveillance
A Brief Report on Outcomes of Stereotactic Ablative Radiotherapy for a Second Primary Lung Cancer: Evidence in Support of Routine CT Surveillance
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DOI：
10.1097/jto.0000000000000218
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发表时间：
2014-08-01
影响因子：
20.4
通讯作者：
Senan, Suresh
中科院分区：
文献类型：
--
作者：
Griffioen, Gwendolyn H. M. J.;Lagerwaard, Frank J.;Senan, Suresh
新的指南建议在肺癌根治性治疗后使用CT监测，因为幸存者每人每年有3-6%的风险发展为第二原发性肺癌。我们对107例第二原发性肺癌患者进行了立体定向消融放射治疗分析，结果显示，3年总生存率（60%）和局部控制率（89%）与初始肺癌相当。尽管73%的患者既往接受过（双）肺叶切除术，但毒性并不常见。我们的研究结果表明，CT监测也适用于可能不适合或不愿意接受手术的患者。
New guidelines recommend the use of CT surveillance after a curative treatment for lung cancer as survivors have a 3-6% risk per person year of developing a second primary lung cancer. Our analysis of 107 patients with second primary lung cancer treated by stereotactic ablative radiotherapy showed a comparable 3 years overall survival (60%) and local control rate (89%) as for an initial lung cancer. Toxicity was uncommon, despite the fact that 73% of patients had undergone a prior (bi) lobectomy. Our findings indicate that CT surveillance is also appropriate in patients who may be unfit, or unwilling, to undergo surgery.