Previous Use of Alcohol, Cigarettes, and Marijuana and Subsequent Abuse of Prescription Opioids in Young Adults
Previous Use of Alcohol, Cigarettes, and Marijuana and Subsequent Abuse of Prescription Opioids in Young Adults
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DOI：
10.1016/j.jadohealth.2012.06.010
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发表时间：
2013-02-01
影响因子：
7.6
通讯作者：
Hoff, Rani A.
中科院分区：
文献类型：
--
作者：
Fiellin, Lynn E.;Tetrault, Jeanette M.;Hoff, Rani A.
目的：处方类阿片类药物的滥用有所增加，特别是在年轻人中。目前的研究探索了青春期酒精、香烟和/或大麻的使用与青春期随后的处方阿片类药物滥用之间的关系。方法：我们使用了20062008次全国药物使用与健康调查中居住在社区的个人的人口/临床数据。我们使用Logistic回归分析，对这些特征进行了调整，以检验既往饮酒、吸烟或大麻使用是否与随后滥用处方阿片类药物的可能性增加有关。结果：在18-25岁的调查人口中(n=6496)，12%的人报告目前滥用处方阿片类药物。对于这一人群，既往药物使用的流行率为57%的酒精，56%的香烟和34%的大麻。我们发现，以前饮酒与年轻男性随后滥用处方阿片类药物有关，但与年轻女性无关。在男性和女性中，以前使用大麻与随后滥用处方阿片类药物有关的可能性是以前没有使用大麻的2.5倍。我们发现，在年轻男孩中，所有以前使用过的药物(酒精、香烟和大麻)，但只有年轻女孩以前使用过大麻，与青壮年期间随后滥用处方阿片类药物的可能性增加相关。结论：以前使用酒精、香烟和大麻都与18-25岁男性目前滥用处方阿片类药物有关，但只有大麻使用与年轻女性随后滥用处方阿片类药物有关。针对早期药物滥用的预防努力可能有助于遏制处方阿片类药物的滥用。(C)2013年青少年健康和医学学会。版权所有。
Purpose: There has been an increase in the abuse of prescription opioids, especially in younger individuals. The current study explores the association between alcohol, cigarette, and/or marijuana use during adolescence and subsequent abuse of prescription opioids during young adulthood.Methods: We used demographic/clinical data from community-dwelling individuals in the 20062008 National Survey on Drug Use and Health. We used logistic regression analyses, adjusted for these characteristics, to test whether having previous alcohol, cigarette, or marijuana use was associated with an increased likelihood of subsequently abusing prescription opioids.Results: Twelve percent of the survey population of 18-25 year olds (n = 6,496) reported current abuse of prescription opioids. For this population, prevalence of previous substance use was 57% for alcohol, 56% for cigarettes, and 34% for marijuana. We found previous alcohol use was associated with the subsequent abuse of prescription opioids in young men but not young women. Among both men and women, previous marijuana use was 2.5 times more likely than no previous marijuana to be associated with subsequent abuse of prescription opioids. We found that among young boys, all previous substance use (alcohol, cigarettes, and marijuana), but only previous marijuana use in young girls, was associated with an increased likelihood of subsequent abuse of prescription opioids during young adulthood.Conclusions: Previous alcohol, cigarette, and marijuana use were each associated with current abuse of prescription opioids in 18-25-year-old men, but only marijuana use was associated with subsequent abuse of prescription opioids in young women. Prevention efforts targeting early substance abuse may help to curb the abuse of prescription opioids. (C) 2013 Society for Adolescent Health and Medicine. All rights reserved.