Listing and Transplanting Adults With Congenital Heart Disease

Listing and Transplanting Adults With Congenital Heart Disease
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DOI:
10.1161/circulationaha.110.960260
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发表时间:
2011-02-22
期刊:
影响因子:
37.8
通讯作者:
Chen, Jonathan M.
Chen, Jonathan M.
中科院分区:
医学1区
文献类型:
--
作者:
Davies, Ryan R.;Russo, Mark J.;Chen, Jonathan M.

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Background-An increasing number of patients with congenital heart disease (CHD) are reaching adulthood and may require heart transplantation. The survival of these patients after listing and transplantation has not been evaluated.Methods and Results-A total of 41 849 patients (aged >18 years) were listed for primary transplantation during 1995-2009. Patients with a history of CHD (n = 1035; 2.5%) were compared with those with other causes (non-CHD group) (n = 40 814; 97.5%); 26 055 (62.3%) reached transplantation and were subdivided into those with (reoperation group; n = 10 484; 40.2%) and without (nonreoperation group; n = 15 571; 59.8%) a previous sternotomy. Survival on the waiting list was similar between groups, but mechanical ventricular assistance was not associated with superior survival to transplantation among CHD patients. CHD patients were more likely to have body mass index