Relationship between rhythmic motor activity and plasma luteinizing hormone in ovariectomized sheep.
Relationship between rhythmic motor activity and plasma luteinizing hormone in ovariectomized sheep.
复制标题
去势羊节律性运动活动与血浆黄体生成素的关系。
DOI：
10.1159/000123187
复制
发表时间：
1981
影响因子：
4.1
通讯作者：
P. Malven
中科院分区：
文献类型：
--
作者：
Dennis D. Rasmussen;P. Malven
研究了卵巢切除母羊黄体生成素 (LH) 间歇性分泌的时间与超日休息-活动周期的关系。每只羊被封闭在一个室中，连续监测它们的身体活动，并通过延伸到室外部的插管每隔 5 分钟收集用于 LH 分析的血液样本。通过功率谱分析对 5 小时采样试验期间运动活动和血浆 LH 的同步曲线进行节律性分析。通过交叉光谱分析检查运动活动节律和血浆 LH 之间的时间关系。活性和血浆 LH 水平都倾向于有节奏地波动，并且 LH 和活性的节律性的发生是相关的。 LH 节律和活动节律的周期（频率的倒数）在各个试验中高度相关，并且在整个试验中它们的平均值均为 36 分钟。交叉谱分析表明，血浆 LH 在运动活动最大或最小时往往会升高。这些结果表明 LH 的节律性分泌与休息-活动周期之间存在关系，这可能基于独立夹带到共同计时节律的机制。
The timing of the episodic secretion of luteinizing hormone (LH) in ovariectomized ewes was investigated with respect to an ultradian rest-activity cycle. Individual sheep were enclosed in a chamber where their physical activity was continuously monitored, and blood samples for LH analysis were collected at 5-min intervals through a cannula extending to the exterior of the chamber. Concurrent profiles of motor activity and plasma LH during 5-hour sampling trials were each analyzed for rhythmicity by power spectral analysis. Temporal relationships between rhythms in motor activity and plasma LH were examined by cross-spectral analysis. Both activity and plasma LH levels tended to fluctuate rhythmically, and the occurrences of rhythmicity for LH and for activity were correlated. The periods (reciprocal of frequencies) for the LH rhythms and activity rhythms were highly correlated within individuals trials, and across trials they both averaged 36 min. Cross-spectral analysis indicated that plasma LH tended to be elevated during times of either greatest or least motor activity. These results suggest a relationship between the rhythmic secretion of LH and the rest-activity cycle which may be based on a mechanism of independent entrainment to a common timing rhythm.