Neurocognitive Processes Implicated in Adolescent Suicidal Thoughts and Behaviors: Applying an RDoC Framework for Conceptualizing Risk.

Neurocognitive Processes Implicated in Adolescent Suicidal Thoughts and Behaviors: Applying an RDoC Framework for Conceptualizing Risk.
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青少年自杀想法和行为中涉及的神经认知过程:应用 RDoC 框架来概念化风险。

DOI:
10.1007/s40473-019-00194-1
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发表时间:
2019
影响因子:
1.7
通讯作者:
Auerbach,RandyP
Auerbach,RandyP
中科院分区:
--
文献类型:
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作者:
Stewart,JeremyG;Polanco-Roman,Lillian;Duarte,CristianeS;Auerbach,RandyP

文献摘要

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综述目的识别青春期性病的危险因素对预防自杀至关重要。在这篇综述中,我们采用研究领域标准(RDoC)框架来综合与青少年STB相关的关键神经认知过程-认知控制,奖励反应/评价和负紧迫感的研究。决策)缺陷始终与自杀企图有关。相比之下,较少的研究探讨了正价系统。相对于健康对照组,青少年与以前的STB可能会表现出迟钝的神经反应的奖励和价值奖励少,但研究结果需要复制。最后,消极的紧迫感,这可能会跨越认知控制和积极的效价系统内的子域,与最近的自杀企图在唯一的研究,直接测试这种association.SummaryFew的研究已经检查了神经认知功能的青少年STB,尽管本研究的相关性,以检测自杀风险。我们建议,未来的研究纳入相关的神经认知过程和STBs的发展背景。
Purpose of ReviewIdentifying risk factors for STBs during adolescence is essential for suicide prevention. In this review, we employ the Research Domain Criteria (RDoC) framework to synthesize studies on key neurocognitive processes—cognitive control, reward responsiveness/valuation, and negative urgency—relevant to adolescent STBs.Recent FindingsWithin subdomains of cognitive control, studies of inhibition/suppression and updating/maintenance were mixed, while response selection (i.e., decision-making) deficits were consistently associated with suicide attempts. Fewer studies, by comparison, have probed the Positive Valence Systems. Relative to healthy controls, adolescents with prior STBs may show a blunted neural response to rewards and value rewards less, but findings require replication. Finally, negative urgency, which may span subdomains within both cognitive control and the Positive Valence Systems, was associated with recent suicide attempts in the only study to directly test this association.SummaryFew studies have examined neurocognitive functioning in relation to adolescent STBs, despite the relevance of this research to detecting suicide risk. We recommend that future studies incorporate developmental contexts relevant to both neurocognitive processes and STBs.