Percutaneous sclerotherapy of venous malformations of the head and neck using sodium tetradecyl sulphate (Sotradecol)
Percutaneous sclerotherapy of venous malformations of the head and neck using sodium tetradecyl sulphate (Sotradecol)
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DOI：
10.3109/02844319709085481
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发表时间：
1997-06-01
影响因子：
--
通讯作者：
Edstrom, S
中科院分区：
文献类型：
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作者：
Siniluoto, TMJ;Svendsen, PA;Edstrom, S
38例面部、颈部和舌静脉畸形患者接受了经皮硬化治疗，直接穿刺并向病变中滴注十四烷基硫酸钠（Sotradecol）（33-67%溶液，与造影剂混合）。每例患者接受1至7次治疗（平均2.2次），3例患者随后接受重建手术。在对随访问卷作出回答的34名患者中，23名患者（68%）的晚期结果为极好或良好，8名患者为中度，3名患者无变化，1名患者恶化。与我们之前使用乙醇栓塞此类畸形的经验相比，Sotradecol的结果略差。有一个严重的并发症，单侧视力丧失的病人与一个大的畸形，延伸到眼眶。总之，Sotradecol经皮硬化疗法是治疗头颈部静脉畸形的有效方法。仔细的计划对于降低治疗风险至关重要。
Thirty-eight patients with venous malformations of the face, neck, and tongue underwent percutaneous sclerotherapy with direct puncture and instillation of sodium tetradecyl sulphate (Sotradecol) (33-67% solution, mixed with contrast material) into the lesions. Each patient underwent from one to seven treatment sessions (mean 2.2), followed by reconstructive surgery in three cases. Of the 34 patients who responded to the follow-up questionnaire, the late results were excellent or good in 23 patients (68%), moderate in eight, unchanged in three, and were worse in one. Compared with our previous experience of embolisation of such malformations with ethanol, the results with Sotradecol were slightly worse. There was one serious complication, unilateral loss of vision in a patient with a large malformation that extended to the orbit. In conclusion, percutaneous sclerotherapy with Sotradecol is effective treatment for venous malformations of the head and neck. Careful planning is essential to reduce the risks of the treatment.