Characteristics of peripheral nerve regeneration following a second nerve injury and repair
Characteristics of peripheral nerve regeneration following a second nerve injury and repair
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DOI：
10.3109/10731199.2011.652259
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发表时间：
2012-07
期刊：
影响因子：
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通讯作者：
Yanhua Wang;Peixun Zhang;Xiaofeng Yin;Jian-ping Peng;Y. Kou;Zhenjun Zhang;Dianying Zhang;B. Jiang
中科院分区：
文献类型：
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作者：
Yanhua Wang;Peixun Zhang;Xiaofeng Yin;Jian-ping Peng;Y. Kou;Zhenjun Zhang;Dianying Zhang;B. Jiang
摘要在周围神经再生过程中，单个神经元可以再生，并在再生的远端残端维持多个侧支。此外，部分新生芽可通过髓鞘再生逐渐成熟，并长入远端靶器官发挥生理功能。我们的研究发现，当新生神经纤维受到第二次损伤时，再生远端残端可以再生并在第二再生远端残端中保持一个以上的侧支。新生神经有助于神经功能的恢复，但神经功能的恢复并不完全。
Abstract During the process of peripheral nerve regeneration, a single neuron can regenerate and maintain more than one collateral in a regenerative distal stump. Furthermore, some of the new shoots can mature gradually through remyelination and grow into the remote target organ to play a physiological function. Our study found that when neonatal nerve fibers are subjected to a second injury, the regenerative distal stump can regenerate and maintain more than one collateral in the second regenerative distal stump. The neonatal nerve contributed to the functional recovery of the nerve, but the restoration of nerve function was not complete.