NEUROANATOMICAL CORRELATES OF SKIN-CONDUCTANCE ORIENTING IN NORMAL HUMANS - A MAGNETIC-RESONANCE-IMAGING STUDY
NEUROANATOMICAL CORRELATES OF SKIN-CONDUCTANCE ORIENTING IN NORMAL HUMANS - A MAGNETIC-RESONANCE-IMAGING STUDY
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DOI：
10.1111/j.1469-8986.1991.tb01991.x
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发表时间：
1991-09-01
期刊：
影响因子：
3.7
通讯作者：
SHEARD, C
中科院分区：
文献类型：
--
作者：
RAINE, A;REYNOLDS, GP;SHEARD, C
虽然鲜为人知的是，在完整的正常人皮肤电导定向的神经解剖学基础，有限的文献对动物和人类的神经和临床疾病牵连前额叶颞/杏仁核，脑桥脑区介导的皮肤电导定向。本研究涉及这些结构的区域，使用磁共振成像技术的皮肤电导定向反应在17个正常人，以测试假设，这些兴奋性结构的更大的面积将与更多的定向反应。左右手皮肤电传导定向与左右前额区（r = 0.44 - 0.60）、脑桥区（r = 0.43 - 0.54）和左侧（而非右侧）颞/杏仁核区（r = 0.47 - 0.53）显著相关。没有观察到与皮肤电导活动无关的区域（小脑，非额叶皮质区），内侧前额叶皮质或第三脑室的关系。这似乎是第一个研究大脑结构与皮肤电导定向在完整的正常人。虽然初步在目前的时间，这些结果牵连前额，脑桥，颞/杏仁核地区的调解皮肤电导定向在正常人。
Although little is known about the neuroanatomical basis of skin conductance orienting in intact normal humans, the limited literature on animals and humans with neurological and clinical disorders implicate prefrontal temporal/amygdala, and pons brain areas in mediating skin conductance orienting. This study relates area of these structures using magnetic resonance imaging techniques to skin conductance orienting responses in 17 normal humans in order to test hypotheses that larger area of these excitatory structures will be associated with more orienting responses. Left and right hand skin conductance orienting was significantly associated with left and right prefrontal area (r = .44-.60), area of the pons (r = .43-.54), and left but not right temporal/amygdala area (r = .47-.53). No relationships were observed with areas thought to be unrelated to skin conductance activity (cerebellum, nonfrontal cortical area), medial prefrontal cortex, or the third ventricle. This appears to be the first study relating brain structure to skin conductance orienting in intact normal humans. Although preliminary at the present time, these results implicate prefrontal, pons, and temporal/amygdala areas in the mediation of skin conductance orienting in normal humans.