Quantitative three-dimensional elasticity imaging from quasi-static deformation: a phantom study
Quantitative three-dimensional elasticity imaging from quasi-static deformation: a phantom study
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DOI：
10.1088/0031-9155/54/3/019
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发表时间：
2009-02-07
影响因子：
3.5
通讯作者：
Oberai, Assad A.
中科院分区：
文献类型：
--
作者：
Richards, Michael S.;Barbone, Paul E.;Oberai, Assad A.
我们提出了一种方法来成像和量化的剪切弹性模量的三维（3D）乳腺组织体积保持在压缩条件下类似的临床乳腺X射线摄影系统。制造组织模型以模拟乳房组织的超声和机械特性。在这些体模中创建刚性损伤，其相对于背景的尺寸和模量对比度值在临床感兴趣的值范围内。一个二维的超声系统，垂直扫描，被用来获取这些幻影的三维图像，因为它们被压缩。根据在不同压缩状态下采集的两个3D超声图像，测量三维位移矢量场。然后使用测量的位移场来求解逆问题，假设体模材料是不可压缩的线性弹性固体，以恢复成像体积内的剪切模量分布。然后将重建值与通过直接机械测试独立测量的值进行比较。
We present a methodology to image and quantify the shear elastic modulus of three-dimensional (3D) breast tissue volumes held in compression under conditions similar to those of a clinical mammography system. Tissue phantoms are made to mimic the ultrasonic and mechanical properties of breast tissue. Stiff lesions are created in these phantoms with size and modulus contrast values, relative to the background, that are within the range of values of clinical interest. A two-dimensional ultrasound system, scanned elevationally, is used to acquire 3D images of these phantoms as they are held in compression. From two 3D ultrasound images, acquired at different compressed states, a three-dimensional displacement vector field is measured. The measured displacement field is then used to solve an inverse problem, assuming the phantom material to be an incompressible, linear elastic solid, to recover the shear modulus distribution within the imaged volume. The reconstructed values are then compared to values measured independently by direct mechanical testing.