De novo genome assembly of Akanthomyces muscarius, a biocontrol agent of insect agricultural pests.
De novo genome assembly of Akanthomyces muscarius, a biocontrol agent of insect agricultural pests.
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DOI：
10.1099/acmi.0.000568.v3
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发表时间：
2023
影响因子：
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通讯作者：
Sharma, Manmohan D
中科院分区：
文献类型：
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作者：
Erdos, Zoltan;Studholme, David John;Raymond, Ben;Sharma, Manmohan D
昆虫病原真菌赤色菌是农业中常用的防治害虫的真菌。除了作为一种重要的商业生物防治剂外，它还提供了一种在实验室环境中研究宿主-病原体相互作用和毒力进化的潜在模型。在这里，我们描述了第一个高质量的muscarius基因组序列。我们使用长、短读测序方法组装了一个36.1 Mb的序列，N50为4.9 Mb。基因组注释预测了12347个基因，基于核心Hypocrealen基因集的完整性为96.6%。本研究的高质量组装和注释为今后对这一重要商业物种的研究提供了必要的工具。
The entomopathogenic fungus Akanthomyces muscarius is commonly used in agriculture to manage insect pests. Besides its use as a commercially important biological control agent, it also presents a potential model for studying host–pathogen interactions and the evolution of virulence in a laboratory setting. Here, we describe the first high-quality genome sequence for A. muscarius. We used long- and short-read sequencing to assemble a sequence of 36.1 Mb with an N50 of 4.9 Mb. Genome annotation predicted 12347 genes, with 96.6 % completeness based on the core Hypocrealen gene set. The high-quality assembly and annotation of A. muscarius presented in this study provides an essential tool for future research on this commercially important species.