Nonspecific interstitial pneumonia pattern as pulmonary involvement of rheumatoid arthritis
Nonspecific interstitial pneumonia pattern as pulmonary involvement of rheumatoid arthritis
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DOI：
10.1007/s00296-004-0527-0
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发表时间：
2005-12-01
影响因子：
4
通讯作者：
Ueda, R
中科院分区：
文献类型：
--
作者：
Yoshinouchi, T;Ohtsuki, Y;Ueda, R
对16例类风湿关节炎（RA）患者的肺部病变进行了病理分析。他们包括6名女性和10名男性，中位年龄为67.5岁，根据美国风湿病协会修订的标准进行诊断。所有患者均进行了肺部高分辨率计算机断层扫描（HRCT），7例患者有明显的蜂窝状形成。组织病理学诊断为普通型间质性肺炎（UIP）7例，非特异性间质性肺炎/纤维化（NSIP）7例，UIP/NSIP混合型2例。NSIP患者HRCT上无明显蜂窝样改变。总之，本研究表明，NSIP模式也是一个重要的组织学分类间质性肺炎与RA。
The pathologic patterns of lung involvement were evaluated in 16 patients with rheumatoid arthritis (RA). They consisted of six females and ten males, with a median age of 67.5 years and diagnosed according to the American Rheumatism Association revised criteria. High-resolution computed tomography (HRCT) of the lungs was performed in all patients, and honeycomb formation was apparent in seven. Histopathologically, seven patients were diagnosed with usual interstitial pneumonia (UIP) pattern, seven with nonspecific interstitial pneumonia/fibrosis (NSIP) pattern, and two with UIP/NSIP hybrid pattern. There were no apparent honeycomb formations on HRCT in patients diagnosed with NSIP pattern. In conclusion, the present study demonstrates that NSIP pattern is also a significant histologic classification of interstitial pneumonia associated with RA.