SCHIZOPHRENIC SYNDROMES, COGNITIVE PERFORMANCE AND NEUROLOGICAL DYSFUNCTION

SCHIZOPHRENIC SYNDROMES, COGNITIVE PERFORMANCE AND NEUROLOGICAL DYSFUNCTION
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DOI:
10.1017/s0033291700012976
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发表时间:
1987-02-01
影响因子:
6.9
通讯作者:
LIDDLE, PF
LIDDLE, PF
中科院分区:
医学1区
文献类型:
--
作者:
LIDDLE, PF

文献摘要

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在一组慢性精神分裂症患者的样本中,发现一组包括语言贫乏和缺乏自发运动的症状与概念性思维、物体命名和长期记忆测试中的糟糕表现有关,也与皮质神经学症状有关。第二组症状包括形式思维障碍和不适当的影响,与注意力、即时回忆和单词学习测试中的糟糕表现以及皮质神经学症状有关。研究结果表明,这两种综合征与额叶内两个不同部位的功能障碍有关。第三组症状,包括各种妄想和幻觉,与图形-背景感知能力差有关,可能反映了颞叶功能障碍。
In a sample of chronic schizophrenic patients, a group of symptoms which included poverty of speech and lack of spontaneous movement was found to be associated with poor performance in tests of conceptual thinking, object naming and long-term memory, and also with cortical neurological signs. A second group of symptoms which included formal thought disorder and inappropriate affect was associated with poor performance in tests of concentration, immediate recall and word learning, and with cortical neurological signs. The findings suggest that these two syndromes are associated with dysfunction at two different sites within the frontal lobes. A third group of symptoms, comprising various delusions and hallucinations, was associated with poor figure-ground perception, and might reflect temporal lobe dysfunction.