Co-occurrence of aflatoxins and ochratoxin A in dried fruits in Iran: Dietary exposure risk assessment
Co-occurrence of aflatoxins and ochratoxin A in dried fruits in Iran: Dietary exposure risk assessment
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DOI：
10.1016/j.fct.2017.05.046
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发表时间：
2017-08-01
影响因子：
4.3
通讯作者：
Sant'Ana, Anderson S.
中科院分区：
文献类型：
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作者：
Heshmati, Ali;Zohrevand, Tahereh;Sant'Ana, Anderson S.
在这项研究中，黄曲霉毒素（AFs）和赭曲霉毒素A（OTA）在88个样品从伊朗的市场，包括干桑葚，枣，无花果，杏的污染水平进行了评估。估计暴露范围（莫伊）以评估从膳食中摄入黄曲霉毒素B-1（AF B（1））和OTA的风险。桑葚、红枣、无花果和杏中AFB（1）的检出率分别为45.5%、40.9%、59.1%和81.8%。虽然受污染的枣（2.61 μ g/kg）、无花果（3.43 μ g/kg）和杏（2.91 μ g/kg）样品中的平均总AFs含量低于欧洲联盟（EU）规定的最高限值（4 μ g/kg），但干桑葚样品的污染水平较高（4.12 μ g/kg）。同时检出OTA和AFs的样品分别为4份（18.9%）、2份（9.1%）、4份（18.2%）和10份（45.5%）。根据计算的莫伊，伊朗通过食用干果摄入AF对消费者健康构成潜在风险。在桑葚、枣、无花果和杏中OTA的检出率分别为45.45%、22.72%、45.45%和50%。然而，所有类型的干果中的OTA水平均低于欧盟法规中的推荐水平（10微克/千克）和莫伊> 10000，这表明消费者没有毒理学问题。(C)2017爱思唯尔有限公司版权所有
In this study, the contamination levels of aflatoxins (AFs) and ochratoxin A (OTA) in 88 collected samples from Iran's market including dried mulberry, date, fig, and apricot were evaluated. The margin of exposure (MOE) was estimated to assess the risk of dietary intake of aflatoxin B-1 (AFB(1)) and OTA. The incidence of AFB(1) in dried mulberry, date, fig and apricot samples was 45.5, 40.9, 59.1, and 81.8%, respectively. Although the mean total AFs content in contaminated samples of date (2.61 mu g/kg), fig (3.43 mu g/kg) and apricot (2.91 mu g/kg) was lower than the maximum limit set in the European Union (EU) (4 mu g/kg), dried mulberry samples showed a higher contamination level (4.12 mu g/kg). The co-occurrence of OTA and AFs were noted in 4 (18.9%), 2 (9.1%), 4 (18.2%), and 10 (45.5%) in the dried mulberry, date, fig and apricot samples, respectively. Based on the calculated MOE, the dietary exposure to AFs through the consumption of dried fruit in Iran poses a potential risk to consumer health. OTA was detected in 45.45%, 22.72%, 45.45%, and 50% of mulberry, date, fig and apricot samples, respectively. However, OTA levels in all types of dried fruit were below recommended level in EU regulation (10 mu g/kg) and MOE > 10000, representing no toxicological concerns for consumers. (C) 2017 Elsevier Ltd. All rights reserved.