Amygdala central nucleus lesions disrupt increments, but not decrements, in conditioned stimulus processing.

Amygdala central nucleus lesions disrupt increments, but not decrements, in conditioned stimulus processing.
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杏仁核中央核损伤会扰乱条件刺激处理的增量,但不会扰乱减量。

DOI:
10.1037//0735-7044.107.2.246
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发表时间:
1993
影响因子:
1.9
通讯作者:
Gallagher,M
Gallagher,M
中科院分区:
医学4区
文献类型:
--
作者:
Holland,PC;Gallagher,M

文献摘要

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通过2个大鼠实验,研究了杏仁核中央核(CN)神经毒性损伤对食欲巴甫洛夫条件反射中CS关联能力变化的影响。在实验1中,CN病变对预暴露于该线索(潜伏抑制)产生的CS的关联性降低没有影响。在实验2中,当CS与另一个线索之间存在不一致的预测关系时,通常会观察到,CN病变阻止了CS关联性的增强。结果支持先前的说法,即杏仁核CN参与巴甫洛夫条件反射中CSs加工的广泛增量变化,而不是递减变化。(PsycINFO数据库记录(c) 2016 APA,版权所有)
The effects of neurotoxic lesions of the amygdala central nucleus (CN) on changes in the associability of a CS in appetitive Pavlovian conditioning were examined in 2 experiments with rats. In Exp 1, CN lesions had no effect on the reduction in the associability of a CS produced by preexposure to that cue (latent inhibition). In Exp 2, CN lesions prevented the enhancement of the associability of a CS that is normally observed when an inconsistent predictive relation is arranged between that CS and another cue. Results support previous claims that the amygdala CN is involved in broad-based incremental, but not decremental, changes in the processing of CSs in Pavlovian conditioning.(PsycINFO Database Record (c) 2016 APA, all rights reserved)