Laboratory information system requirements to manage the COVID-19 pandemic: A report from the Belgian national reference testing center
Laboratory information system requirements to manage the COVID-19 pandemic: A report from the Belgian national reference testing center
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DOI：
10.1093/jamia/ocaa081
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发表时间：
2020-08-01
影响因子：
6.4
通讯作者：
Goveia, Jermaine
中科院分区：
文献类型：
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作者：
Weemaes, Matthias;Martens, Steven;Goveia, Jermaine
目的：本研究旨在描述实验室信息系统 (LIS) 功能的开发、实施和要求，以管理 2019 年冠状病毒病 (COVID-19) 大流行期间的检测订购、注册、样本流和结果报告。材料和方法：我们大型（>12 000 000 次检测/年）学术医院实验室是比利时国家严重急性呼吸综合征冠状病毒 2 (SARS-CoV-2) 检测参考中心。自疫情爆发以来，我们已在标准常规测试的同时进行了总计超过 25,000 次 SARS-CoV-2 聚合酶链反应测试。危机初期成立了一个 LIS 实施团队，致力于开发工具以消除主要位于分析前和分析后阶段的瓶颈。结果：我们概述了与管理 COVID-19 危机期间增加的测试需求相关的 LIS 功能的设计、实施和要求，包括测试订购工具、集成到计算机化提供商订单输入模块中的标准化订单集、运输要求通知、基于数字元数据表格的自动分诊以及建立包含其他实验室和初级保健医生联系方式的数据库，以便能够自动报告。我们还描述了我们的数据挖掘方法以及向管理机构和其他政策制定者报告可操作的每日汇总统计数据的方法。结论：快速开发、灵活的可扩展 LIS 功能及其有意义的用途减轻了实验室人员的管理负担，并缩短了 SARS-CoV-2 测试的周转时间。在 COVID-19 危机之后，维持有利于快速采用有意义的 LIS 工具的环境非常重要。
Objective: The study sought to describe the development, implementation, and requirements of laboratory information system (LIS) functionality to manage test ordering, registration, sample flow, and result reporting during the coronavirus disease 2019 (COVID-19) pandemic.Materials and Methods: Our large (>12 000 000 tests/y) academic hospital laboratory is the Belgian National Reference Center for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) testing. We have performed a moving total of >25 000 SARS-CoV-2 polymerase chain reaction tests in parallel to standard routine testing since the start of the outbreak. A LIS implementation team dedicated to develop tools to remove the bottlenecks, primarily situated in the pre- and postanalytical phases, was established early in the crisis.Results: We outline the design, implementation, and requirements of LIS functionality related to managing increased test demand during the COVID-19 crisis, including tools for test ordering, standardized order sets integrated into a computerized provider order entry module, notifications on shipping requirements, automated triaging based on digital metadata forms, and the establishment of databases with contact details of other laboratories and primary care physicians to enable automated reporting. We also describe our approach to data mining and reporting of actionable daily summary statistics to governing bodies and other policymakers.Conclusions: Rapidly developed, agile extendable LIS functionality and its meaningful use alleviates the administrative burden on laboratory personnel and improves turnaround time of SARS-CoV-2 testing. It will be important to maintain an environment that is conducive for the rapid adoption of meaningful LIS tools after the COVID-19 crisis.